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S1PR5 anticorps (N-Term)

S1PR5 Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache) WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775524
  • Antigène Voir toutes S1PR5 Anticorps
    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
    Épitope
    • 15
    • 15
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 50
    • 36
    • 36
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Porc, Boeuf (Vache)
    Hôte
    • 81
    • 1
    • 1
    Lapin
    Clonalité
    • 82
    • 1
    Polyclonal
    Conjugué
    • 26
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp S1PR5 est non-conjugé
    Application
    • 45
    • 35
    • 26
    • 26
    • 13
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MESGLLRPAP VSEVIVLHYN YTGKLRGARY QPGAGLRADA VVCLAVCAFI
    Homologie
    Cow: 80%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against EDG8. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human EDG8
    Top Product
    Discover our top product S1PR5 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 147 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bock, Pfalzgraff, Weindl: "Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells." dans: Journal of dermatological science, Vol. 82, Issue 1, pp. 9-17, (2016) (PubMed).

  • Antigène
    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
    Autre désignation
    EDG8 (S1PR5 Produits)
    Synonymes
    anticorps EDG8, anticorps Edg-8, anticorps S1P5, anticorps SPPR-1, anticorps SPPR-2, anticorps fd11a07, anticorps wu:fd11a07, anticorps zgc:92296, anticorps edg-8, anticorps edg8, anticorps s1p5, anticorps sppr-1, anticorps sppr-2, anticorps xts1p5, anticorps Edg8, anticorps lpB4, anticorps zgc:158362, anticorps sphingosine-1-phosphate receptor 5, anticorps sphingosine-1-phosphate receptor 5a, anticorps sphingosine-1-phosphate receptor 5b, anticorps S1PR5, anticorps s1pr5a, anticorps s1pr5, anticorps S1pr5, anticorps s1pr5b
    Sujet
    EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
    Alias Symbols: Edg-8, S1P5, S1PR5, SPPR-1, SPPR-2, EDG8
    Protein Interaction Partner: TP63, GNA12, GNAO1, GNAI1, SGPP1,
    Protein Size: 147
    Poids moléculaire
    16 kDa
    ID gène
    53637
    NCBI Accession
    NM_003339
    UniProt
    Q9H228
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