S1PR5 anticorps (N-Term)

N° du produit ABIN2775524

Détail du produit anti-S1PR5 anticorps

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MESGLLRPAP VSEVIVLHYN YTGKLRGARY QPGAGLRADA VVCLAVCAFI

Homologie: Cow: 80%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EDG8. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human EDG8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 147 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-S1PR5 (ABIN2775524)

Bock, Pfalzgraff, Weindl: "Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells." dans: Journal of dermatological science, Vol. 82, Issue 1, pp. 9-17, (2016) (PubMed).

Détails sur S1PR5

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Autre désignation: EDG8 (S1PR5 Produits)

Synonymes: anticorps EDG8, anticorps Edg-8, anticorps S1P5, anticorps SPPR-1, anticorps SPPR-2, anticorps fd11a07, anticorps wu:fd11a07, anticorps zgc:92296, anticorps edg-8, anticorps edg8, anticorps s1p5, anticorps sppr-1, anticorps sppr-2, anticorps xts1p5, anticorps Edg8, anticorps lpB4, anticorps zgc:158362, anticorps sphingosine-1-phosphate receptor 5, anticorps sphingosine-1-phosphate receptor 5a, anticorps sphingosine-1-phosphate receptor 5b, anticorps S1PR5, anticorps s1pr5a, anticorps s1pr5, anticorps S1pr5, anticorps s1pr5b

Sujet: EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Alias Symbols: Edg-8, S1P5, S1PR5, SPPR-1, SPPR-2, EDG8
Protein Interaction Partner: TP63, GNA12, GNAO1, GNAI1, SGPP1,
Protein Size: 147

Poids moléculaire: 16 kDa

ID gène: 53637

NCBI Accession: NM_003339

UniProt: Q9H228