ATG4A anticorps (Middle Region)
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- Antigène Voir toutes ATG4A Anticorps
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Porc, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ATG4A est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PQSLGALGGK PNNAYYFIGF LGDELIFLDP HTTQTFVDTE ENGTVNDQTF
- Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against ATG4A. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ATG4A
- Top Product
- Discover our top product ATG4A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 398 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." dans: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).
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Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." dans: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).
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- Antigène
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
- Autre désignation
- ATG4A (ATG4A Produits)
- Synonymes
- anticorps apg4a, anticorps autl2, anticorps F6E13.27, anticorps APG4A, anticorps zgc:111958, anticorps Aut2a, anticorps AUTL2, anticorps AI627006, anticorps AV169859, anticorps Apg4a, anticorps Atg4al, anticorps Autl2, anticorps Atg4a, anticorps autophagy related 4A cysteine peptidase L homeolog, anticorps autophagy related 4A cysteine peptidase, anticorps Peptidase family C54 protein, anticorps ATG4 autophagy related 4 homolog A (S. cerevisiae), anticorps autophagy related 4A, cysteine peptidase, anticorps atg4a.L, anticorps ATG4A, anticorps AT2G44140, anticorps atg4a, anticorps Atg4a
- Sujet
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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.
Alias Symbols: APG4A, AUTL2
Protein Interaction Partner: CDKL3, GABARAPL1, GABARAPL2, ATG101, MAP1LC3B,
Protein Size: 398 - Poids moléculaire
- 45 kDa
- ID gène
- 115201
- NCBI Accession
- NM_052936, NP_443168
- UniProt
- Q8WYN0
- Pathways
- Autophagy
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