ACLY anticorps (Middle Region)

N° du produit ABIN2775558

Détail du produit anti-ACLY anticorps

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Mouton, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACLY est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LRSAYDSTME TMNYAQIRTI AIIAEGIPEA LTRKLIKKAD QKGVTIIGPA

Homologie: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ACLY. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ACLY

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1101 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ACLY (ABIN2775558)

Infantino, Iacobazzi, Palmieri, Menga: "ATP-citrate lyase is essential for macrophage inflammatory response." dans: Biochemical and biophysical research communications, Vol. 440, Issue 1, pp. 105-11, (2013) (PubMed).

Détails sur ACLY

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Autre désignation: ACLY (ACLY Produits)

Synonymes: anticorps ACLY, anticorps DDBDRAFT_0205389, anticorps DDBDRAFT_0235360, anticorps DDB_0205389, anticorps DDB_0235360, anticorps ACL, anticorps BcDNA:LD21334, anticorps CG8322, anticorps DmATPCL, anticorps Dmel\\CG8322, anticorps anon-WO0140519.179, anticorps dATPCL, anticorps l(2)01466, anticorps l(2)k09217, anticorps n(2)k09217, anticorps ATPCL, anticorps CLATP, anticorps A730098H14Rik, anticorps AW538652, anticorps Clatp, anticorps acly, anticorps cb722, anticorps zgc:92008, anticorps ATP citrate lyase, anticorps ATP citrate lyase S homeolog, anticorps ATP-citrate synthase, anticorps citrate synthase, mitochondrial, anticorps atp-citrate synthase, anticorps ATP citrate lyase a, anticorps ACLY, anticorps acly.S, anticorps LOC587157, anticorps acly, anticorps ATPCL, anticorps LOC5564509, anticorps CpipJ_CPIJ010291, anticorps Bm1_26245, anticorps ACL, anticorps Acly, anticorps aclya

Sujet: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety
Alias Symbols: ACL, ATPCL, CLATP
Protein Interaction Partner: UBC, UBR4, SIRT2, HUWE1, ISG15, KAT2B, SUMO2, SUMO3, STAU1, SUMO1, NEDD8, MDM2, ASB15, WWOX, TRIM25, MAGED2, BAG3, PPP6C, NCL, MCM6, MCM2, KPNA4, KPNA2, PRMT1, CDKN2A, SRRT, UBD, FN1, APP, SHC1, CUL3, CAND1, CUL2, SIRT7, UL27, HDAC5, TERF2, TERF1, GSK3B,
Protein Size: 1101

Poids moléculaire: 121 kDa

ID gène: 47

NCBI Accession: NM_001096, NP_001087

UniProt: P53396

Pathways: L'effet Warburg