Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Pannexin 2 anticorps (N-Term)

PANX2 Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775571
  • Antigène Voir toutes Pannexin 2 (PANX2) Anticorps
    Pannexin 2 (PANX2)
    Épitope
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 21
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval
    Hôte
    • 20
    • 4
    Lapin
    Clonalité
    • 20
    • 4
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    Cet anticorp Pannexin 2 est non-conjugé
    Application
    • 18
    • 15
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    GTVLVPILLV TLVFTKNFAE EPIYCYTPHN FTRDQALYAR GYCWTELRDA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PANX2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human PANX2
    Top Product
    Discover our top product PANX2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 633 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wicki-Stordeur, Boyce, Swayne: "Analysis of a pannexin 2-pannexin 1 chimeric protein supports divergent roles for pannexin C-termini in cellular localization." dans: Cell communication & adhesion, Vol. 20, Issue 3-4, pp. 73-9, (2013) (PubMed).

    Mylvaganam, Zhang, Wu, Zhang, Samoilova, Eubanks, Carlen, Poulter: "Hippocampal seizures alter the expression of the pannexin and connexin transcriptome." dans: Journal of neurochemistry, Vol. 112, Issue 1, pp. 92-102, (2010) (PubMed).

    Swayne, Sorbara, Bennett: "Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment." dans: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24977-86, (2010) (PubMed).

    Lai, Bechberger, Naus: "Pannexin2 as a novel growth regulator in C6 glioma cells." dans: Oncogene, Vol. 28, Issue 49, pp. 4402-8, (2009) (PubMed).

    Wang, Streeter, Liu, Zhao: "Identification and characterization of pannexin expression in the mammalian cochlea." dans: The Journal of comparative neurology, Vol. 512, Issue 3, pp. 336-46, (2008) (PubMed).

  • Antigène
    Pannexin 2 (PANX2)
    Autre désignation
    PANX2 (PANX2 Produits)
    Sujet
    PANX2 belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties.The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties.
    Alias Symbols: hPANX2, PX2
    Protein Size: 633
    Poids moléculaire
    70 kDa
    ID gène
    56666
    NCBI Accession
    NM_052839, NP_443071
    UniProt
    Q96RD6
Vous êtes ici:
Support technique