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COX IV anticorps (N-Term)

COX4I1 Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775574
  • Antigène Voir toutes COX IV (COX4I1) Anticorps
    COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))
    Épitope
    • 16
    • 14
    • 12
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 121
    • 54
    • 45
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin
    Hôte
    • 87
    • 36
    • 2
    • 2
    Lapin
    Clonalité
    • 86
    • 41
    Polyclonal
    Conjugué
    • 63
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COX IV est non-conjugé
    Application
    • 108
    • 40
    • 37
    • 27
    • 26
    • 23
    • 19
    • 19
    • 14
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    AISTSVCVRA HESVVKSEDF SLPAYMDRRD HPLPEVAHVK HLSASQKALK
    Homologie
    Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against COX4I1. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human COX4I1
    Top Product
    Discover our top product COX4I1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 169 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hwang, Dornbos, Steidemann, Dunivin, Rizzo, LaPres: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." dans: Toxicology and applied pharmacology, (2016) (PubMed).

    Geerling, Boon, van der Zon, van den Berg, van den Hoek, Lombès, Princen, Havekes, Rensen, Guigas: "Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice." dans: Diabetes, Vol. 63, Issue 3, pp. 880-91, (2014) (PubMed).

    Snyder, Wang, Patton, Arosio, Levi, Earley, Allen, Connor: "Mitochondrial ferritin in the substantia nigra in restless legs syndrome." dans: Journal of neuropathology and experimental neurology, Vol. 68, Issue 11, pp. 1193-9, (2009) (PubMed).

  • Antigène
    COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))
    Autre désignation
    COX4I1 (COX4I1 Produits)
    Synonymes
    anticorps COX4, anticorps COX4-1, anticorps COXIV, anticorps mg:bb02d03, anticorps zgc:110058, anticorps GB20012, anticorps AL024441, anticorps Cox4, anticorps Cox4a, anticorps cox4, anticorps cox4i1, anticorps coxiv, anticorps BcDNA:AT07685, anticorps CG10396, anticorps COX IV, anticorps CX41, anticorps CX42, anticorps Dmel\CG10396, anticorps IV, anticorps cytochrome c oxidase subunit 4I1, anticorps cytochrome c oxidase subunit IV isoform 1, anticorps cytochrome c oxidase subunit 4 isoform 1, mitochondrial, anticorps cytochrome c oxidase polypeptide IV, anticorps cytochrome c oxidase subunit IV, anticorps cytochrome c oxidase subunit 4i1, anticorps cytochrome c oxidase subunit IV isoform 1 S homeolog, anticorps Cytochrome c oxidase subunit 4-like, anticorps COX4I1, anticorps cox4i1, anticorps LOC412396, anticorps Cox4I1, anticorps LOC780848, anticorps BMEII0322, anticorps RSal33209_1582, anticorps SJAG_00976, anticorps HMPREF0733_11926, anticorps Cox4i1, anticorps cox4i1.S, anticorps COX4L
    Sujet
    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4I1 is the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
    Alias Symbols: COX4, COXIV, MGC72016, COX4-1
    Protein Interaction Partner: SDCBP, COX1, env, APP, UBC, ICT1, TMBIM4, NELFCD,
    Protein Size: 169
    Poids moléculaire
    19 kDa
    ID gène
    1327
    NCBI Accession
    NM_001861, NP_001852
    UniProt
    P13073
    Pathways
    Proton Transport
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