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PARD6A anticorps (N-Term)

PARD6A Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cheval, Cobaye, Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775615
  • Antigène Voir toutes PARD6A Anticorps
    PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
    Épitope
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 24
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Boeuf (Vache), Cheval, Cobaye, Chien
    Hôte
    • 24
    • 2
    • 1
    Lapin
    Clonalité
    • 27
    Polyclonal
    Conjugué
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PARD6A est non-conjugé
    Application
    • 15
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MARPQRTPAR SPDSIVEVKS KFDAEFRRFA LPRASVSGFQ EFSRLLRAVH
    Homologie
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PARD6A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6A
    Top Product
    Discover our top product PARD6A Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 345 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
    Autre désignation
    PARD6A (PARD6A Produits)
    Synonymes
    anticorps PARD6A, anticorps 0710008C04Rik, anticorps 2610010A15Rik, anticorps PAR6alpha, anticorps Par-6, anticorps Par6, anticorps Par6c, anticorps TAX40, anticorps Tip-40, anticorps Par-6a, anticorps Par6a, anticorps PAR-6A, anticorps PAR6, anticorps PAR6C, anticorps TIP-40, anticorps par-6 partitioning defective 6 homolog alpha (C. elegans), anticorps par-6 family cell polarity regulator alpha, anticorps Partitioning defective protein 6, anticorps PARD6A, anticorps Pard6a, anticorps par-6
    Sujet
    This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
    Protein Interaction Partner: PRKCI, WDR83, PRKCZ, FBXO31, PARD3, UBC, TUBG1, ARHGAP17, VHL, MAP2K5, TJP1, SMURF1, TGFB1, WDR92, PARD6B, PDRG1, RPAP3, MARK4, PIH1D1, SUGT1, YWHAZ, YWHAH, LLGL1, LLGL2, MARK2, CDC42, CRB3, ECT2, PLCB1, RHOQ, PRKCH, RAC1, CDH5, PLCB3, TGFBR1, TCP10, PRKC
    Protein Size: 345
    Poids moléculaire
    37 kDa
    ID gène
    50855
    NCBI Accession
    NM_001037281, NP_001032358
    UniProt
    Q3TY70
    Pathways
    Cell-Cell Junction Organization
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