AMOTL1 anticorps (N-Term)

N° du produit ABIN2775636

Détail du produit anti-AMOTL1 anticorps

Antigène: AMOTL1 (Angiomotin Like 1 (AMOTL1))

Épitope: N-Term

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMOTL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LTQEDPQMVY QSARQEPQGQ EHQVDNTVME KQVRSTQPQQ NNEELPTYEE

Homologie: Cow: 93%, Dog: 79%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%

Attributs du produit: This is a rabbit polyclonal antibody against AMOTL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AMOTL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 956 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-AMOTL1 (ABIN2775636)

Skouloudaki, Walz: "YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation." dans: PLoS ONE, Vol. 7, Issue 4, pp. e35735, (2012) (PubMed).

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." dans: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Détails sur AMOTL1

Antigène: AMOTL1 (Angiomotin Like 1 (AMOTL1))

Autre désignation: AMOTL1 (AMOTL1 Produits)

Sujet: AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
Alias Symbols: JEAP
Protein Interaction Partner: WWOX, SUZ12, NEDD4, HECW2, AMOT, LATS2, YAP1, LATS1, Wwtr1, UBC, Magi1, NEDD4L,
Protein Size: 956

Poids moléculaire: 106 kDa

ID gène: 154810

NCBI Accession: NM_130847, NP_570899

UniProt: Q8IY63