Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ube3a anticorps (Middle Region)

ube3a Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Boeuf (Vache) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775648
  • Antigène Voir toutes ube3a Anticorps
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    Épitope
    • 15
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 51
    • 11
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Boeuf (Vache)
    Hôte
    • 46
    • 5
    Lapin
    Clonalité
    • 46
    • 5
    Polyclonal
    Conjugué
    • 28
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ube3a est non-conjugé
    Application
    • 27
    • 17
    • 16
    • 13
    • 13
    • 9
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    AKNGPDTERL PTSHTCFNVL LLPEYSSKEK LKERLLKAIT YAKGFGML
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against UBE3A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human UBE3A
    Top Product
    Discover our top product ube3a Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 875 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    ube3a (Ubiquitin Protein Ligase E3A (ube3a))
    Autre désignation
    UBE3A (ube3a Produits)
    Synonymes
    anticorps ANCR, anticorps AS, anticorps E6-AP, anticorps EPVE6AP, anticorps HPVE6A, anticorps DDBDRAFT_0188760, anticorps DDBDRAFT_0302447, anticorps DDB_0188760, anticorps DDB_0302447, anticorps ube3a, anticorps im:7140733, anticorps zgc:92173, anticorps 4732496B02, anticorps 5830462N02Rik, anticorps A130086L21Rik, anticorps Hpve6a, anticorps mKIAA4216, anticorps As, anticorps CG6190, anticorps Dmel\\CG6190, anticorps Dube3a, anticorps UBE3A, anticorps dUBE3A, anticorps das, anticorps dube3A, anticorps dube3a, anticorps MGC69536, anticorps UME3A, anticorps ubiquitin protein ligase E3A, anticorps ubiquitin-protein ligase E3A, anticorps Ubiquitin protein ligase E3A, anticorps ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog, anticorps ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome), anticorps UBE3A, anticorps ube3a, anticorps LOC100194730, anticorps Ube3a, anticorps ube3a.S, anticorps Eint_040430
    Sujet
    UBE3A is an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.
    Alias Symbols: ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A
    Protein Interaction Partner: KLHL38, UBE2D1, UBB, TP53, TAT, AFG3L1P, ATG9A, ASAP3, AHSP, UBE3A, UBC, MEOX2, MAGEA8, JADE1, YOD1, UBE2L3, UBE2D3, PSMD14, SHFM1, ARNTL, LPP, HSF1, DR1, BTF3L4, LRSAM1, P3H1, NPLOC4, IPO11, DBNL, LSM1, ARPC1B, METTL1, SACS, ARC, RAD23A, PTPN3, CEBPA, SC
    Protein Size: 875
    Poids moléculaire
    101 kDa
    ID gène
    7337
    NCBI Accession
    NM_000462, NP_000453
    UniProt
    Q05086
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
Vous êtes ici:
Support technique