AMFR anticorps (C-Term)

N° du produit ABIN2775669

Détail du produit anti-AMFR anticorps

Antigène: AMFR (Autocrine Motility Factor Receptor (AMFR))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMFR est non-conjugé

Application: Western Blotting (WB)

Séquence: FGEVEVEPSE VEDFEARGSR FSKSADERQR MLVQRKDELL QQARKRFLNK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against AMFR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human AMFR

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 482 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AMFR

Antigène: AMFR (Autocrine Motility Factor Receptor (AMFR))

Autre désignation: AMFR (AMFR Produits)

Synonymes: anticorps GP78, anticorps RNF45, anticorps gp78, anticorps wu:fi06e06, anticorps wu:fi37e05, anticorps zgc:63893, anticorps rnf45, anticorps autocrine motility factor receptor, anticorps autocrine motility factor receptor L homeolog, anticorps autocrine motility factor receptor a, anticorps autocrine motility factor receptor, amfr, anticorps putative autocrine motility factor receptor, amfr, anticorps AMFR, anticorps Amfr, anticorps amfr.L, anticorps amfra, anticorps amfr, anticorps AaeL_AAEL005881, anticorps CpipJ_CPIJ016043, anticorps Smp_047420

Sujet: Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).[supplied by OMIM].
Alias Symbols: GP78, RNF45
Protein Interaction Partner: VCP, UBE2G1, HSPA5, ERLIN2, INSIG1, HMGCR, DHFR, AMFR, UBE2D1, UBC, GPI, TRIM25, DGAT2, UBE2K, Ube2g2, NPLOC4, HERPUD1, BAG6, MAVS, YOD1, ADRA1D, DERL2, ADRB2, FAF2, SEC61B, RPN1, STT3A, STT3B, AUP1, MDC1, SNED1, DDOST, GET4, UBXN4, UBL4A, CD82, SARAF, IT
Protein Size: 643

Poids moléculaire: 73 kDa

ID gène: 267

NCBI Accession: NM_013446

UniProt: Q9UKV5

Pathways: ER-Nucleus Signaling