UBE2D2 anticorps (Middle Region)
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- Antigène Voir toutes UBE2D2 Anticorps
- UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio), Mouton
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UBE2D2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TIMGPNDSPY QGGVFFLTIH FPTDYPFKPP KVAFTTRIYH PNINSNGSIC
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against UBE2D2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human UBE2D2
- Top Product
- Discover our top product UBE2D2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 147 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
- Autre désignation
- UBE2D2 (UBE2D2 Produits)
- Synonymes
- anticorps E2(17)KB2, anticorps PUBC1, anticorps UBC4, anticorps UBC4/5, anticorps UBCH5B, anticorps 1500034D03Rik, anticorps Ubc2e, anticorps Ube2d2, anticorps ubc4, anticorps ube2d2, anticorps zgc:55886, anticorps E217kB, anticorps ubiquitin conjugating enzyme E2 D2, anticorps ubiquitin-conjugating enzyme E2D 2A, anticorps ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), anticorps ubiquitin-conjugating enzyme E2D 2, anticorps ubiquitin conjugating enzyme E2 D3, anticorps UBE2D2, anticorps Ube2d2a, anticorps ube2d2, anticorps Ube2d2, anticorps UBE2D3
- Sujet
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Protein Interaction Partner: RNF26, CHFR, RBX1, DZIP3, UBA1, UBC, TRAF6, BIRC7, anapc11, ZNRF1, RNF146, MID1, MDM2, BIRC3, FZR1, ITCH, HRD1, CUL3, XIAP, MARCH7, RNF25, UBE2D2, RNF130, UBA6, CBLC, PARK2, TRIM21, KCMF1, RNF135, MUL1, MDM4, TRIM23, STUB1, CBL, UBTD1, RNF38, UBI4, RFFL,
Protein Size: 147 - Poids moléculaire
- 17 kDa
- ID gène
- 7322
- NCBI Accession
- NM_003339, NP_003330
- UniProt
- P62837
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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