CCT4 anticorps (C-Term)

N° du produit ABIN2775694

Détail du produit anti-CCT4 anticorps

Antigène: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Saccharomyces cerevisiae, Chévre, Poisson zèbre (Danio rerio), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCT4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: AFADAMEVIP STLAENAGLN PISTVTELRN RHAQGEKTAG INVRKGGISN

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CCT4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CCT4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 539 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CCT4 (ABIN2775694)

Tarkar, Loges, Slagle, Francis, Dougherty, Tamayo, Shook, Cantino, Schwartz, Jahnke, Olbrich, Werner, Raidt, Pennekamp, Abouhamed, Hjeij, Köhler, Griese, Li, Lemke, Klena, Liu, Gabriel, Tobita et al.: "DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." dans: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).

Machida, Masutani, Kobayashi, Mikami, Nishino, Miyazawa, Imataka: "Reconstitution of the human chaperonin CCT by co-expression of the eight distinct subunits in mammalian cells." dans: Protein expression and purification, Vol. 82, Issue 1, pp. 61-9, (2012) (PubMed).

Détails sur CCT4

Antigène: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Autre désignation: CCT4 (CCT4 Produits)

Synonymes: anticorps zgc:65789, anticorps zgc:77192, anticorps Cct4, anticorps Dmel\\CG5525, anticorps Tcp-1delta, anticorps Tcp1-delta, anticorps cct4, anticorps MGC89275, anticorps CCT4, anticorps DKFZp459D1424, anticorps LOC100225853, anticorps cctd, anticorps CCT-DELTA, anticorps Cctd, anticorps SRB, anticorps 2610204B21Rik, anticorps A45, anticorps C78323, anticorps chaperonin containing TCP1, subunit 4 (delta), anticorps chaperonin containing TCP1 subunit 4, anticorps chaperonin containing TCP1 subunit 4 L homeolog, anticorps CG5525 gene product from transcript CG5525-RA, anticorps chaperonin containing Tcp1, subunit 4 (delta), anticorps T-complex protein 1 subunit delta, anticorps cct4, anticorps CCT4, anticorps cct4.L, anticorps CG5525, anticorps Cct4, anticorps cct-4

Sujet: The CCT (chaperonin containing TCP-1) complex functions as a molecular chaperone in the eukaryotic cytosol. CCT4 interacts with human cyclin E which has been implicated in positive control of the G1/S phase transition.
Alias Symbols: SRB, Cctd, CCT-DELTA
Protein Interaction Partner: HUWE1, TP53, FUS, CDC20, NEDD1, TUBG1, LGALS3BP, UBC, STAU1, MDM2, RFWD2, VRK2, PRPF40A, CCT7, USP9X, VARS, CCT3, CCT6A, FBXO6, UBD, FBXW4, CDK9, CDK5, CDK2, CD81, IGSF8, HDAC11, HDAC3, RPS6KA1, ILK, ICAM1, PAN2, VCAM1, PPP5C, PEX14, NOS2, US3, FAM86B2, C
Protein Size: 539

Poids moléculaire: 58 kDa

ID gène: 10575

NCBI Accession: NM_006430, NP_006421

UniProt: Q53QP9

Pathways: Embryonic Body Morphogenesis