ZYX anticorps (Middle Region)

N° du produit ABIN2775767

Détail du produit anti-ZYX anticorps

Antigène: ZYX (Zyxin (ZYX))

Épitope: Middle Region

Reactivité: Humain, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZYX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ZYX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human ZYX

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 572 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZYX

Antigène: ZYX (Zyxin (ZYX))

Autre désignation: ZYX (ZYX Produits)

Synonymes: anticorps BcDNA:LD06023, anticorps CG32018, anticorps DLim-1, anticorps DmLIM-1, anticorps Dmel\\CG32018, anticorps Lim102EF, anticorps ZYX102, anticorps Zyx102, anticorps Zyx102EF, anticorps lim, anticorps zyx102, anticorps zyxin, anticorps zgc:171680, anticorps ZYX, anticorps zyx, anticorps MGC145270, anticorps ESP-2, anticorps HED-2, anticorps 9530098H06Rik, anticorps R75157, anticorps Zyxin, anticorps zyxin, anticorps zyxin S homeolog, anticorps zyx-1, anticorps Zyx, anticorps zyx, anticorps ZYX, anticorps EDI_201420, anticorps zyx.S

Sujet: TRIM50 is an E3 ubiquitin-protein ligase.Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
Alias Symbols: ESP-2, HED-2
Protein Interaction Partner: RTN4IP1, YPEL3, IMP3, PHF21A, PDLIM5, LIN7A, SUMO1, NEDD8, FAM129B, CORO1B, CAND1, PUF60, PAPOLA, NUDC, SEC23B, SEC24C, HIST1H4A, UGP2, TARS, PXN, GART, GARS, APEH, FN1, HIPK3, VCAM1, UBC, UBL7, UFC1, UBXN7, ZC3H7B, TTLL12, FERMT2, TOMM34, AHCYL1, SSSCA1,
Protein Size: 572

Poids moléculaire: 61 kDa

ID gène: 7791

NCBI Accession: NM_003461, NP_003452

UniProt: Q15942