MIER1 anticorps (Middle Region)

N° du produit ABIN2775813

Détail du produit anti-MIER1 anticorps

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Lapin, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIER1 est non-conjugé

Application: Western Blotting (WB)

Séquence: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MIER1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MIER1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 536 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MIER1

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Autre désignation: MIER1 (MIER1 Produits)

Synonymes: anticorps 4933425I22Rik, anticorps 5830411K19Rik, anticorps mKIAA1610, anticorps mier1, anticorps wu:fb30a02, anticorps zgc:56179, anticorps mi-er1, anticorps ER1, anticorps MI-ER1, anticorps RGD1562337, anticorps MEIR1 treanscription regulator, anticorps MIER1 transcriptional regulator, anticorps mesoderm induction early response 1a, transcriptional regulator, anticorps mesoderm induction early response 1, transcriptional regulator L homeolog, anticorps Mier1, anticorps MIER1, anticorps mier1a, anticorps mier1.L

Sujet: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
Alias Symbols: ER1, MI-ER1, hMI-ER1, RP5-944N15.1
Protein Interaction Partner: TMEM171, SOX2, HDAC2, HDAC1, EHMT2, CDYL, TUBB1, APP, ELAVL1, UBC, CREBBP, SP1,
Protein Size: 536

Poids moléculaire: 49 kDa

ID gène: 57708

NCBI Accession: NM_020948, NP_065999

UniProt: Q8NES5

Pathways: Chromatin Binding