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NRF1 anticorps (Middle Region)

NRF1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chien WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775850
  • Antigène Voir toutes NRF1 Anticorps
    NRF1 (Nuclear Respiratory Factor 1 (NRF1))
    Épitope
    • 15
    • 9
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 71
    • 42
    • 35
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chien
    Hôte
    • 68
    • 5
    Lapin
    Clonalité
    • 60
    • 13
    Polyclonal
    Conjugué
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NRF1 est non-conjugé
    Application
    • 60
    • 29
    • 14
    • 14
    • 12
    • 12
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    WATLQGGEMT IQTTQASEAT QAVASLAEAA VAASQEMQQG ATVTMALNSE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against NRF1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of Human NRF1
    Top Product
    Discover our top product NRF1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 503 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Teodoro, Duarte, Gomes, Varela, Peixoto, Rolo, Palmeira: "Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation." dans: Mitochondrion, Vol. 13, Issue 6, pp. 637-46, (2013) (PubMed).

  • Antigène
    NRF1 (Nuclear Respiratory Factor 1 (NRF1))
    Autre désignation
    NRF1 (NRF1 Produits)
    Synonymes
    anticorps ALPHA-PAL, anticorps C87038, anticorps D6Ertd415e, anticorps SC:BZ3C13.1, anticorps SC:bZ3C13.2, anticorps ube2h, anticorps Nfe2l1_retired, anticorps IBR/F, anticorps NRF1, anticorps alpha-pal, anticorps nrf-1, anticorps LOC100220087, anticorps nuclear respiratory factor 1, anticorps nuclear respiratory factor 1 S homeolog, anticorps NRF1, anticorps Nrf1, anticorps nrf1, anticorps nrf1.S
    Sujet
    This protein homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth.
    Alias Symbols: ALPHA-PAL
    Protein Interaction Partner: POGZ, TRAF2, SP4, FHL2, DYNLL1, CSNK2B, CSNK2A1, UBC, HHV8GK18_gp81, CEBPB, PARP1, PPRC1, MAFF, PPARGC1A, Dynlt1b, CDK1, MRPL57, TFAM,
    Protein Size: 503
    Poids moléculaire
    53 kDa
    ID gène
    4899
    NCBI Accession
    NM_005011, NP_005002
    UniProt
    Q16656
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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