LIMA1 anticorps (Middle Region)

N° du produit ABIN2775866

Détail du produit anti-LIMA1 anticorps

Antigène: LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Cheval, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: GVLAASMEAK ASSQQEKEDK PAETKKLRIA WPPPTELGSS GSALEEGIKM

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against LIMA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human LIMA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 759 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-LIMA1 (ABIN2775866)

Maul, Song, Amann, Gerbin, Pollard, Chang: "EPLIN regulates actin dynamics by cross-linking and stabilizing filaments." dans: The Journal of cell biology, Vol. 160, Issue 3, pp. 399-407, (2003) (PubMed).

Détails sur LIMA1

Antigène: LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))

Autre désignation: LIMA1 (LIMA1 Produits)

Synonymes: anticorps eplin, anticorps LIMA1, anticorps EPLIN, anticorps MGC146397, anticorps SREBP3, anticorps 1110021C24Rik, anticorps 3526402A12Rik, anticorps D15Ertd366e, anticorps Eplin, anticorps LIM domain and actin binding 1, anticorps Lima1, anticorps LIMA1, anticorps lima1

Sujet: This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.
Alias Symbols: EPLIN, SREBP3
Protein Interaction Partner: TP53, UBC, RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, BMI1, LRCH3, YWHAQ, YWHAB, PAN2, YWHAE, FMNL1, PAXIP1, ATP6V1B1, APP, UBXN6, LRRK2, ARRB2, ARRB1, SVIL, YWHAG,
Protein Size: 759

Poids moléculaire: 85 kDa

ID gène: 51474

NCBI Accession: NM_016357, NP_057441

UniProt: Q9UHB6