KLHL3 anticorps (N-Term)

N° du produit ABIN2775874

Détail du produit anti-KLHL3 anticorps

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Lapin, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: CSPYFCAMFT GDMSESKAKK IEIKDVDGQT LSKLIDYIYT AEIEVTEENV

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Attributs du produit: This is a rabbit polyclonal antibody against KLHL3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KLHL3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 587 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KLHL3

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Autre désignation: KLHL3 (KLHL3 Produits)

Synonymes: anticorps 7530408C15Rik, anticorps AI430941, anticorps EG627648, anticorps PHA2D, anticorps RGD1565218, anticorps kelch like family member 3, anticorps kelch-like 3, anticorps kelch-like family member 3, anticorps KLHL3, anticorps Klhl3

Sujet: KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77 % similarity with Drosophila kelch and 89 % similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
Alias Symbols: FLJ40871, KIAA1129, MGC44594, PHA2D
Protein Interaction Partner: WNK4, KLHL12, KLHL3, KEAP1, MORF4L2, CUL3, UBC, C6orf165, WNK3, WNK2, WNK1, RBX1, SLC12A3, ELAVL1, SYNCRIP, SYT2, OPRD1, GNAO1, GNAI1,
Protein Size: 587

Poids moléculaire: 65 kDa

ID gène: 26249

NCBI Accession: NM_017415, NP_059111

UniProt: Q9UH77