TRIOBP anticorps (Middle Region)

N° du produit ABIN2775973

Détail du produit anti-TRIOBP anticorps

Antigène: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Lapin, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIOBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: QIHTKDAVYT LSAMTSGIRR NWIEALRKTV RPTSAPDVTK LSDSNKENAL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TRIOBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRIOBP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 431 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIOBP

Antigène: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Autre désignation: TRIOBP (TRIOBP Produits)

Synonymes: anticorps tara, anticorps DFNB28, anticorps TARA, anticorps dJ37E16.4, anticorps AI428493, anticorps EST478828, anticorps Tara, anticorps mKIAA1662, anticorps TRIO and F-actin binding protein, anticorps TRIO and F-actin-binding protein, anticorps TRIO and F-actin binding protein L homeolog, anticorps TRIO and F-actin binding protein-like, anticorps TRIOBP, anticorps LOC100354753, anticorps triobp.L, anticorps TRIOBPL, anticorps Triobp

Sujet: TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
Alias Symbols: DFNB28, FLJ39315, HRIHFB2122, KIAA1662, TARA, dJ37E16.4
Protein Interaction Partner: POLR1C, IKBKG, GTF2H1, PLK1, ELAVL1, VIM, HECTD3, UBC,
Protein Size: 431

Poids moléculaire: 47 kDa

ID gène: 11078

NCBI Accession: NM_138632, NP_619538

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization