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RFX6 anticorps (Middle Region)

RFX6 Reactivité: Humain, Souris, Cobaye, Cheval, Lapin, Boeuf (Vache), Rat, Chien, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2776023
  • Antigène Voir toutes RFX6 Anticorps
    RFX6 (Regulatory Factor X 6 (RFX6))
    Épitope
    • 5
    • 4
    • 1
    • 1
    Middle Region
    Reactivité
    • 19
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Cobaye, Cheval, Lapin, Boeuf (Vache), Rat, Chien, Poisson zèbre (Danio rerio)
    Hôte
    • 17
    • 2
    Lapin
    Clonalité
    • 19
    Polyclonal
    Conjugué
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RFX6 est non-conjugé
    Application
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LGTRGHSKYH YYGIGIKESS AYYHSVYSGK GLTRFSGSKL KNEGGFTRKY
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against Rfx6. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of MOUSE Rfx6
    Top Product
    Discover our top product RFX6 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    RFX6 (Regulatory Factor X 6 (RFX6))
    Autre désignation
    Rfx6 (RFX6 Produits)
    Synonymes
    anticorps MTFS, anticorps RFXDC1, anticorps dJ955L16.1, anticorps 4930572O07Rik, anticorps Rfxdc1, anticorps regulatory factor X6, anticorps regulatory factor X, 6, anticorps RFX6, anticorps Rfx6
    Sujet
    Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes.
    Protein Size: 524
    Poids moléculaire
    57 kDa
    ID gène
    320995
    Pathways
    Carbohydrate Homeostasis
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