CHRNA4 anticorps (N-Term)
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- Antigène Voir toutes CHRNA4 Anticorps
- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cobaye, Lapin, Chien, Cheval, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CHRNA4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- AEERLLKKLF SGYNKWSRPV ANISDVVLVR FGLSIAQLID VDEKNQMMTT
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against CHRNA4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA4
- Top Product
- Discover our top product CHRNA4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 627 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." dans: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).
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Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." dans: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).
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- Antigène
- CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
- Autre désignation
- CHRNA4 (CHRNA4 Produits)
- Synonymes
- anticorps NACHRA4, anticorps BFNC, anticorps EBN, anticorps EBN1, anticorps NACHR, anticorps NACRA4, anticorps NARAC, anticorps Acra-4, anticorps Acra4, anticorps ENFL1, anticorps neuronal acetylcholine receptor subunit alpha-4, anticorps neuronal acetylcholine receptor subunit alpha-4-like, anticorps cholinergic receptor nicotinic alpha 4 subunit, anticorps cholinergic receptor, nicotinic, alpha 4b, anticorps cholinergic receptor, nicotinic, alpha polypeptide 4, anticorps CpipJ_CPIJ002434, anticorps LOC100368057, anticorps CHRNA4, anticorps chrna4b, anticorps Chrna4
- Sujet
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CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BFNC, EBN, EBN1, NACRA4, NACHR, NACHRA4
Protein Interaction Partner: Ubqln1, CSNK2B, VSNL1, CHRNB4, CHRNB2, YWHAH, CRELD2,
Protein Size: 627 - Poids moléculaire
- 67 kDa
- ID gène
- 1137
- NCBI Accession
- NM_000744, NP_000735
- UniProt
- P43681
- Pathways
- Synaptic Membrane
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