VDAC1 anticorps (C-Term)
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- Antigène Voir toutes VDAC1 Anticorps
- VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Mouton, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp VDAC1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- SAKVNNSSLI GLGYTQTLKP GIKLTLSALL DGKNVNAGGH KLGLGLEFQA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against VDAC1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human VDAC1
- Top Product
- Discover our top product VDAC1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 283 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes." dans: PLoS ONE, Vol. 8, Issue 6, pp. e66478, (2013) (PubMed).
: "Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic." dans: Human molecular genetics, Vol. 21, Issue 21, pp. 4680-702, (2012) (PubMed).
: "Reduced expression of lamin A/C results in modified cell signaling and metabolism coupled with changes in expression of structural proteins." dans: Journal of proteome research, Vol. 8, Issue 11, pp. 5196-211, (2009) (PubMed).
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Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes." dans: PLoS ONE, Vol. 8, Issue 6, pp. e66478, (2013) (PubMed).
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- Antigène
- VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
- Autre désignation
- VDAC1 (VDAC1 Produits)
- Synonymes
- anticorps vdac1, anticorps VDAC1, anticorps 5076, anticorps ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1, anticorps ATVDAC1, anticorps T22N4.9, anticorps T22N4_9, anticorps voltage dependent anion channel 1, anticorps PORIN, anticorps VDAC-1, anticorps AL033343, anticorps Vdac5, anticorps fa13f11, anticorps wu:fa13f11, anticorps zgc:85830, anticorps voltage-dependent anion channel 1 S homeolog, anticorps voltage-dependent anion channel 1, anticorps voltage dependent anion channel 1, anticorps vdac1.S, anticorps vdac1, anticorps VDAC1, anticorps Vdac1
- Sujet
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The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH(-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis.
Alias Symbols: PORIN, VDAC-1
Protein Interaction Partner: UBC, KLHL40, SPRTN, MDM2, ADRB2, ASB14, ASB17, PARK2, BAG3, env, VCAM1, HK1, ATF2, FMNL1, TUBA1B, MDC1, CAV1, Htt, SFXN3, SUGP1, UBAP2, UFM1, ACAD9, MGAT4B, ACAA2, ZMPSTE24, VAPA, ALDH5A1, SF1, VDAC3, VDAC2, UBA52, TIAL1, FLOT2, CDK2, SIRT7, SUMO4, MAPK3,
Protein Size: 283 - Poids moléculaire
- 31 kDa
- ID gène
- 7416
- NCBI Accession
- NM_003374, NP_003365
- UniProt
- Q5FVE7
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