KCNK4 anticorps (N-Term)

N° du produit ABIN2776270

Détail du produit anti-KCNK4 anticorps

Antigène: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Épitope: N-Term

Reactivité: Humain, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNK4 est non-conjugé

Application: Western Blotting (WB)

Séquence: MRSTTLLALL ALVLLYLVSG ALVFRALEQP HEQQAQRELG EVREKFLRAH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Pig: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against KCNK4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNK4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 393 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-KCNK4 (ABIN2776270)

Bogdan, Fitzgibbon, Woolverton, Bethea, Iyo, Stockmeier, Kyle, Austin: "5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques." dans: Neuroscience letters, Vol. 503, Issue 2, pp. 83-6, (2011) (PubMed).

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." dans: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Détails sur KCNK4

Antigène: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Autre désignation: KCNK4 (KCNK4 Produits)

Synonymes: anticorps K2p4.1, anticorps TRAAK, anticorps TRAAK1, anticorps MLZ-622, anticorps TRAAKt, anticorps Tex40, anticorps KT4.1, anticorps potassium two pore domain channel subfamily K member 4, anticorps potassium channel, subfamily K, member 4, anticorps KCNK4, anticorps Kcnk4

Sujet: Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. KCNK4 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. It homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: K2p4.1, TRAAK, TRAAK1
Protein Interaction Partner: DIDO1, RPL14,
Protein Size: 393

Poids moléculaire: 43 kDa

ID gène: 50801

NCBI Accession: NM_033310, NP_201567

UniProt: Q9NYG8