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PITX2 anticorps (N-Term)

PITX2 Reactivité: Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Chien WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2776373
  • Antigène Voir toutes PITX2 Anticorps
    PITX2 (Paired-Like Homeodomain 2 (PITX2))
    Épitope
    • 10
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 58
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Chien
    Hôte
    • 52
    • 5
    • 1
    Lapin
    Clonalité
    • 55
    • 3
    Polyclonal
    Conjugué
    • 28
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PITX2 est non-conjugé
    Application
    • 46
    • 38
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    SAVSSSSCHH PQPLAMASVL APGQPRSLDS SKHRLEVHTI SDTSSPEAAE
    Homologie
    Cow: 100%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against PITX2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human PITX2
    Top Product
    Discover our top product PITX2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 324 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hatou, Yoshida, Higa, Miyashita, Inagaki, Okano, Tsubota, Shimmura: "Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/?-catenin signaling." dans: Stem cells and development, Vol. 22, Issue 5, pp. 828-39, (2013) (PubMed).

  • Antigène
    PITX2 (Paired-Like Homeodomain 2 (PITX2))
    Autre désignation
    PITX2 (PITX2 Produits)
    Synonymes
    anticorps ARP1, anticorps Brx1, anticorps IDG2, anticorps IGDS, anticorps IGDS2, anticorps IHG2, anticorps IRID2, anticorps Otlx2, anticorps PTX2, anticorps RGS, anticorps RIEG, anticorps RIEG1, anticorps RS, anticorps 9430085M16Rik, anticorps Brx1a, anticorps Brx1b, anticorps Munc30, anticorps Pitx2a, anticorps Pitx2b, anticorps Pitx2c, anticorps Pitx2cbeta, anticorps Ptx2, anticorps Rieg, anticorps pitx2a, anticorps pitx2c, anticorps zgc:110508, anticorps XPtx2b, anticorps xPtx2, anticorps xpitx2, anticorps arp1, anticorps brx1, anticorps idg2, anticorps igds, anticorps igds2, anticorps ihg2, anticorps irid2, anticorps otlx2, anticorps pitx2-A, anticorps ptx2, anticorps rgs, anticorps rieg, anticorps rieg1, anticorps pitx-2, anticorps pitx2, anticorps paired like homeodomain 2, anticorps paired-like homeodomain transcription factor 2, anticorps paired-like homeodomain 2, anticorps paired like homeodomain 2 S homeolog, anticorps paired like homeodomain 2 L homeolog, anticorps PITX2, anticorps Pitx2, anticorps pitx2, anticorps pitx2.S, anticorps pitx2.L
    Sujet
    The PITX2 gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. Mutations in PITX2 are associated with Axenfeld-Rieger syndrome (ARS), iridogoniodysgenesis syndrome (IGDS), and sporadic cases of Peters anomaly. This protein is involved in the development of the eye, tooth and abdominal organs. It also acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
    Alias Symbols: RS, RGS, ARP1, Brx1, IDG2, IGDS, IHG2, PTX2, RIEG, IGDS2, IRID2, Otlx2, RIEG1
    Protein Interaction Partner: LEF1, Hoxa1, WDR5, SMAD3, HDAC1, CTNNB1, ZNHIT3, TRIM25, HERC5, PDLIM1, PITX2, PROP1, KAT5, Pou1f1, MSX2,
    Protein Size: 324
    Poids moléculaire
    36 kDa
    ID gène
    5308
    NCBI Accession
    NM_000325, NP_000316
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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