NMI anticorps (Middle Region)

N° du produit ABIN2776425

Détail du produit anti-NMI anticorps

Antigène: NMI (N-Myc (And STAT) Interactor (NMI))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMI est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: SFSKSRNGGG EVDRVDYDRQ SGSAVITFVE IGVADKILKK KEYPLYINQT

Homologie: Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against NMI. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NMI

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 307 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NMI

Antigène: NMI (N-Myc (And STAT) Interactor (NMI))

Autre désignation: NMI (NMI Produits)

Synonymes: anticorps fj02e01, anticorps wu:fj02e01, anticorps NMI, anticorps MGC108489, anticorps N-myc and STAT interactor, anticorps N-myc (and STAT) interactor, anticorps N-myc and STAT interactor L homeolog, anticorps NMI, anticorps Nmi, anticorps nmi, anticorps nmi.L

Sujet: NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has high expression in myeloid leukemia cell lines. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: HSPA8, GCSH, GOLGA8EP, HDDC3, C9orf72, TXLNA, TXLNB, CNKSR3, LCA5L, C1orf216, SFR1, TUBA3E, MTMR9, COPS7B, BRMS1, KDM1A, POMZP3, HHLA3, EMILIN1, SNAPC5, MAD2L1BP, NMI, MTMR6, SCEL, TRAF5, UBC, PSMG3, OXR1, EXOSC4, TOLLIP, CYHR1, VPS26A, H1FX, NAA10, TBCD,
Protein Size: 307

Poids moléculaire: 35 kDa

ID gène: 9111

NCBI Accession: NM_004688, NP_004679

UniProt: Q13287