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Nucleolar Protein 6 anticorps (N-Term)

NOL6 Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin, Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2776561
  • Antigène Voir toutes Nucleolar Protein 6 (NOL6) Anticorps
    Nucleolar Protein 6 (NOL6)
    Épitope
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin, Saccharomyces cerevisiae
    Hôte
    • 11
    • 3
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 10
    • 2
    • 1
    • 1
    Cet anticorp Nucleolar Protein 6 est non-conjugé
    Application
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    SRKRTLAEPP AKGLLQPVKL SRAELYKEPT NEELNRLRET EILFHSSLLR
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%
    Attributs du produit
    This is a rabbit polyclonal antibody against NOL6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human NOL6
    Top Product
    Discover our top product NOL6 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1146 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Nucleolar Protein 6 (NOL6)
    Autre désignation
    NOL6 (NOL6 Produits)
    Synonymes
    anticorps NRAP, anticorps UTP22, anticorps bA311H10.1, anticorps nrap, anticorps utp22, anticorps AA410091, anticorps Nrap, anticorps nucleolar protein 6, anticorps nucleolar protein 6 L homeolog, anticorps nucleolar protein family 6 (RNA-associated), anticorps NOL6, anticorps Nol6, anticorps nol6.L
    Sujet
    NOL6 is a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
    Alias Symbols: FLJ21959, MGC14896, MGC14921, MGC20838, NRAP, UTP22, bA311H10.1
    Protein Interaction Partner: UBC, SIAH1, LIN28A, RNF2, BMI1, EED, SIRT7, SUMO2, SUMO1, G3BP1,
    Protein Size: 1146
    Poids moléculaire
    127 kDa
    ID gène
    65083
    NCBI Accession
    NM_022917, NP_075068
    UniProt
    Q9H6R4
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