Nucleolar Protein 6 anticorps (N-Term)
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- Antigène Voir toutes Nucleolar Protein 6 (NOL6) Anticorps
- Nucleolar Protein 6 (NOL6)
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin, Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Nucleolar Protein 6 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- SRKRTLAEPP AKGLLQPVKL SRAELYKEPT NEELNRLRET EILFHSSLLR
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%
- Attributs du produit
- This is a rabbit polyclonal antibody against NOL6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NOL6
- Top Product
- Discover our top product NOL6 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1146 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Nucleolar Protein 6 (NOL6)
- Autre désignation
- NOL6 (NOL6 Produits)
- Synonymes
- anticorps NRAP, anticorps UTP22, anticorps bA311H10.1, anticorps nrap, anticorps utp22, anticorps AA410091, anticorps Nrap, anticorps nucleolar protein 6, anticorps nucleolar protein 6 L homeolog, anticorps nucleolar protein family 6 (RNA-associated), anticorps NOL6, anticorps Nol6, anticorps nol6.L
- Sujet
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NOL6 is a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
Alias Symbols: FLJ21959, MGC14896, MGC14921, MGC20838, NRAP, UTP22, bA311H10.1
Protein Interaction Partner: UBC, SIAH1, LIN28A, RNF2, BMI1, EED, SIRT7, SUMO2, SUMO1, G3BP1,
Protein Size: 1146 - Poids moléculaire
- 127 kDa
- ID gène
- 65083
- NCBI Accession
- NM_022917, NP_075068
- UniProt
- Q9H6R4
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