MSH6 anticorps (N-Term)

N° du produit ABIN2776759

Détail du produit anti-MSH6 anticorps

Antigène: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSH6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ISDSESDIGG SDVEFKPDTK EEGSSDEISS GVGDSESEGL NSPVKVARKR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MSH6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MSH6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1360 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MSH6 (ABIN2776759)

Wedrén, Lovmar, Humphreys, Magnusson, Melhus, Syvänen, Kindmark, Landegren, Fermér, Stiger, Persson, Baron, Weiderpass: "Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." dans: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).

Détails sur MSH6

Antigène: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Autre désignation: MSH6 (MSH6 Produits)

Synonymes: anticorps GTBP, anticorps GTMBP, anticorps HNPCC5, anticorps HSAP, anticorps p160, anticorps cb326, anticorps wu:fb36c12, anticorps LOC100227810, anticorps AU044881, anticorps AW550279, anticorps Gtmbp, anticorps mutS homolog 6, anticorps mutS homolog 6 (E. coli), anticorps DNA mismatch repair protein, anticorps MSH6, anticorps msh6, anticorps Msh6

Sujet: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide bind
Alias Symbols: GTBP, HNPCC5, HSAP
Protein Interaction Partner: BRCA1, UBC, SUMO2, PCNA, POLK, SAMHD1, GANAB, HYOU1, SUPT5H, XRCC6, ATP6V1B2, UBD, HDAC11, MSH2, CSNK2A1, SUPT16H, MSH3, MLH1, PMS2, RAD9A, RAD1, MUTYH, HUS1, SLX4, CUL3, NEDD8, FBXO25, SIRT7, XRCC5, PRKDC, BLM, TP53, RAD51, PMS1, SMARCAD1, CHAF1A, DTL, S
Protein Size: 1360

Poids moléculaire: 153 kDa

ID gène: 2956

NCBI Accession: NM_000179, NP_000170

UniProt: P52701

Pathways: Réparation de l'ADN, Chromatin Binding, Production of Molecular Mediator of Immune Response