MSH2 anticorps (N-Term)
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- Antigène Voir toutes MSH2 Anticorps
- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Cobaye, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Lapin, Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MSH2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- KMSAVDGQRQ VGVGYVDSIQ RKLGLCEFPD NDQFSNLEAL LIQIGPKECV
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against MSH2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human MSH2
- Top Product
- Discover our top product MSH2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 586 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Autre désignation
- MSH2 (MSH2 Produits)
- Synonymes
- anticorps COCA1, anticorps FCC1, anticorps HNPCC, anticorps HNPCC1, anticorps LCFS2, anticorps AI788990, anticorps wu:fc06b02, anticorps wu:fc13e09, anticorps zgc:55333, anticorps ATMSH2, anticorps MUTS homolog 2, anticorps msh2, anticorps mutS homolog 2, anticorps mutS homolog 2 (E. coli), anticorps MUTS homolog 2, anticorps mutS homolog 2 L homeolog, anticorps MutS protein homolog 2, anticorps MSH2, anticorps Msh2, anticorps msh2, anticorps msh2.L
- Sujet
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MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
Alias Symbols: FCC1, COCA1, HNPCC, LCFS2, HNPCC1
Protein Interaction Partner: ESR1, BRCA1, SUMO2, RPA3, RPA2, RPA1, REV1, POLK, DPYSL3, ATP6V1B2, CUL2, XRCC5, SUPT5H, STAT3, ST13, PDE3A, NRD1, JUP, XRCC6, SEC23A, HDAC6, PCNA, MSH3, MSH6, ERCC4, ERCC1, gag-pol, UBC, SUPT16H, SEPT9, SRSF10, SRSF11, SART1, SMARCA5, TOP2B, SRSF7, SRSF5
Protein Size: 586 - Poids moléculaire
- 64 kDa
- ID gène
- 4436
- NCBI Accession
- NM_000251
- UniProt
- P43246
- Pathways
- Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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