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RAGE anticorps (N-Term)

Name: RAGE anticorps (N-Term)
SKU: ABIN2776831
Price: 521.33 EUR
Availability: InStock

AGER Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval, Porc WB Hôte: Lapin Polyclonal unconjugated

WB Suggested Anti-AGER Antibody Titration: 0. (RAGE anticorps (N-Term))

Host: Mouse Target Name: AGER Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml (RAGE anticorps (N-Term))

Host: Rabbit Target Name: AGER Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1ug/ml (RAGE anticorps (N-Term))

Lanes : Lane 1: 10ug of hRAGE HEK-293 lysateLane 2: 10ug of mRAGE HEK-293 lysate Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti-rabbit-HRP Secondary Antibody Dilution : 1:2500 Gene Name : AGER Submitted by : Barry Hudson (RAGE anticorps (N-Term))

4 images

N° du produit ABIN2776831

Fiche de données

Antigène Voir toutes RAGE (AGER) Anticorps

RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
Épitope
20

16

16

12

9

9

8

7

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reactivité
151

84

63

6

4

3

2

2

2

1

1

1
Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval, Porc
Hôte
139

11

4

3

2
Lapin
Anticorps secondaires appropriés
Clonalité
136

22

1
Polyclonal
Conjugué
66

11

11

10

8

5

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1
Cet anticorp RAGE est non-conjugé
Application
119

67

51

33

27

26

21

11

8

8

7

3

2

1

1

1
Western Blotting (WB)

Séquence

FLPAVGIQDE GIFRCQAMNR NGKETKSNYR VRVYQIPGKP EIVDSASELT

Specificité

The immunizing peptide sequence is 100 % homologous to all four isoforms of AGER.

Homologie

Cow: 100%, Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit

This is a rabbit polyclonal antibody against AGER. It was validated on Western Blot using a cell lysate as a positive control.

Purification

Affinity Purified

Immunogène

The immunogen is a synthetic peptide directed towards the N terminal region of human AGER

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anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 151-250) antibody
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anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-404) antibody
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AGER Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

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anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 206-234) antibody
AGER Reactivité: Humain WB, IF Hôte: Lapin Polyclonal RB21217 unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 29-59), (N-Term) antibody
AGER Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB04825-04826 unconjugated

Indications d'application

Optimal working dilutions should be determined experimentally by the investigator.

Commentaires

Antigen size: 342 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid repeated freeze-thaw cycles.

Stock

-20 °C

Stockage commentaire

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Antigène

RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Autre désignation

AGER (AGER Produits)

Synonymes

anticorps RAGE, anticorps AGER, anticorps advanced glycosylation end-product specific receptor, anticorps advanced glycosylation end product-specific receptor, anticorps MAPK/MAK/MRK overlapping kinase, anticorps AGER, anticorps Ager, anticorps LOC719012

Sujet

AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.
Alias Symbols: MGC22357, RAGE
Protein Size: 342

Poids moléculaire

36 kDa

ID gène

177

NCBI Accession

NM_172197, NP_751947

UniProt

Q15109

Pathways

Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins