MARCO anticorps (C-Term)

N° du produit ABIN2776891

Détail du produit anti-MARCO anticorps

Antigène: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MARCO est non-conjugé

Application: Western Blotting (WB)

Séquence: GPAGVKGEQG SPGLAGPKGA PGQAGQKGDQ GVKGSSGEQG VKGEKGERGE

Homologie: Horse: 86%, Human: 100%, Mouse: 85%, Rat: 85%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MARCO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MARCO

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 520 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MARCO

Antigène: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Autre désignation: MARCO (MARCO Produits)

Synonymes: anticorps AI323439, anticorps Ly112, anticorps Scara2, anticorps SCARA2, anticorps macrophage receptor with collagenous structure, anticorps MARCO, anticorps Marco

Sujet: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
Alias Symbols: SCARA2
Protein Interaction Partner: SCGB3A2, SCGB3A1,
Protein Size: 520

Poids moléculaire: 53 kDa

ID gène: 8685

NCBI Accession: NM_006770, NP_006761

UniProt: Q9UEW3

Pathways: Activation of Innate immune Response