RAGE anticorps (C-Term)
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- Antigène Voir toutes RAGE (AGER) Anticorps
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RAGE est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- RIRAGNSSPG PGDPGRPGDS RPAHWGHLVA KAATPRRGEE GPRKPGGRGG
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against AGER. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human AGER
- Top Product
- Discover our top product AGER Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 342 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Autre désignation
- AGER (AGER Produits)
- Synonymes
- anticorps RAGE, anticorps AGER, anticorps advanced glycosylation end-product specific receptor, anticorps advanced glycosylation end product-specific receptor, anticorps MAPK/MAK/MRK overlapping kinase, anticorps AGER, anticorps Ager, anticorps LOC719012
- Sujet
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AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: MGC22357, RAGE
Protein Size: 342 - Poids moléculaire
- 38 kDa
- ID gène
- 177
- NCBI Accession
- NM_172197, NP_751947
- UniProt
- A2BFI7
- Pathways
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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