ALAS2 anticorps (C-Term)

N° du produit ABIN2776924

Détail du produit anti-ALAS2 anticorps

Antigène: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Mouton, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALAS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: PTVPRGEELL RLAPSPHHSP QMMEDFVEKL LLAWTAVGLP LQDVSVAACN

Homologie: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against ALAS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ALAS2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 550 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ALAS2 (ABIN2776924)

Chien, Chang, Lee, Su, Wu: "Non-genomic immunosuppressive actions of progesterone inhibits PHA-induced alkalinization and activation in T cells." dans: Journal of cellular biochemistry, Vol. 99, Issue 1, pp. 292-304, (2006) (PubMed).

Détails sur ALAS2

Antigène: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Autre désignation: ALAS2 (ALAS2 Produits)

Synonymes: anticorps anh1, anticorps asb, anticorps xlsa, anticorps ALAS-E, anticorps ALASE, anticorps ANH1, anticorps ASB, anticorps XLDPP, anticorps XLEPP, anticorps XLSA, anticorps alas-e, anticorps cb1063, anticorps sau, anticorps sauternes, anticorps ALAS, anticorps Alas-2, anticorps 5'-aminolevulinate synthase 2, anticorps aminolevulinate, delta-, synthase 2, anticorps aminolevulinic acid synthase 2, erythroid, anticorps alas2, anticorps ALAS2, anticorps Alas2, anticorps alas2.L

Sujet: ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: ANH1, ASB, XLSA, ALASE, XLDPP, XLEPP, ALAS-E
Protein Interaction Partner: BANP, GRB2, SUCLA2, RABGGTB,
Protein Size: 550

Poids moléculaire: 60 kDa

ID gène: 212

NCBI Accession: NM_001037967, NP_001033056

UniProt: P22557

Pathways: Transition Metal Ion Homeostasis