FECH anticorps (N-Term)
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- Antigène Voir toutes FECH Anticorps
- FECH (Ferrochelatase (FECH))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FECH est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LDRDLMTLPI QNKLAPFIAK RRTPKIQEQY RRIGGGSPIK IWTSKQGEGM
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against FECH. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human FECH
- Top Product
- Discover our top product FECH Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 429 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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siRNA-mediated knockdown of the heme synthesis and degradation pathways: modulation of treatment effect of 5-aminolevulinic acid-based photodynamic therapy in urothelial cancer cell lines." dans: Photochemistry and photobiology, Vol. 85, Issue 4, pp. 1020-7, (2009) (PubMed).
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siRNA-mediated knockdown of the heme synthesis and degradation pathways: modulation of treatment effect of 5-aminolevulinic acid-based photodynamic therapy in urothelial cancer cell lines." dans: Photochemistry and photobiology, Vol. 85, Issue 4, pp. 1020-7, (2009) (PubMed).
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- Antigène
- FECH (Ferrochelatase (FECH))
- Autre désignation
- FECH (FECH Produits)
- Synonymes
- anticorps AI894116, anticorps Fcl, anticorps fch, anticorps zgc:109851, anticorps EPP, anticorps FCE, anticorps CG2098, anticorps Dmel\\CG2098, anticorps GB15952, anticorps ferrochelatase L homeolog, anticorps ferrochelatase, anticorps Ferrochelatase, anticorps ferrochelatase, mitochondrial, anticorps ferrochelatase HemH, anticorps ferrochelatase (predicted), anticorps fech.L, anticorps hemH, anticorps Fech, anticorps FECH, anticorps fech, anticorps FeCH, anticorps LOC409922, anticorps hem15, anticorps APH_RS01140
- Sujet
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Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EPP, FCE
Protein Interaction Partner: PPP2R1A, UBC, NEDD8, MDM2, FBXO6, gag-pol, COPS5, COPS6, CUL3, ELAVL1, MINOS1, MME, USP42, USP20, ABCB7, FECH,
Protein Size: 429 - Poids moléculaire
- 47 kDa
- ID gène
- 2235
- NCBI Accession
- NM_001012515, NP_001012533
- UniProt
- Q8NAN0
- Pathways
- Transition Metal Ion Homeostasis
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