CRH anticorps (C-Term)
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- Antigène Voir toutes CRH Anticorps
- CRH (Corticotropin Releasing Hormone (CRH))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris, Chien, Porc, Mouton, Boeuf (Vache), Lapin, Cobaye, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CRH est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM
- Homologie
- Cow: 85%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against CRH. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CRH
- Top Product
- Discover our top product CRH Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CRH (Corticotropin Releasing Hormone (CRH))
- Autre désignation
- CRH (CRH Produits)
- Synonymes
- anticorps CRF, anticorps Gm1347, anticorps crf, anticorps crh, anticorps zgc:101864, anticorps CRH, anticorps corticoliberin, anticorps crhb, anticorps crh.1-a, anticorps crha, anticorps corticotropin releasing hormone, anticorps corticotropin releasing hormone b, anticorps corticotropin releasing hormone S homeolog, anticorps corticotropin releasing hormone L homeolog, anticorps Crh, anticorps CRH, anticorps crhb, anticorps crh, anticorps crh.S, anticorps crh.L
- Sujet
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Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
Alias Symbols: CRF
Protein Interaction Partner: KRT31, CRHR1, CRH, CRHR2,
Protein Size: 196 - Poids moléculaire
- 21 kDa
- ID gène
- 1392
- NCBI Accession
- NM_000756, NP_000747
- UniProt
- P06850
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
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