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GSTM2 anticorps (N-Term)

GSTM2 Reactivité: Humain, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777010
  • Antigène Voir toutes GSTM2 Anticorps
    GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))
    Épitope
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 21
    • 14
    • 8
    Humain, Poisson zèbre (Danio rerio)
    Hôte
    • 23
    • 5
    Lapin
    Clonalité
    • 23
    • 5
    Polyclonal
    Conjugué
    • 18
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GSTM2 est non-conjugé
    Application
    • 18
    • 13
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    TQSNAILRYI ARKHNLCGES EKEQIREDIL ENQFMDSRMQ LAKLCYDPDF
    Homologie
    Human: 100%, Zebrafish: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against GSTM2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human GSTM2
    Top Product
    Discover our top product GSTM2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Antigen size: 218 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))
    Autre désignation
    GSTM2 (GSTM2 Produits)
    Synonymes
    anticorps GSTA4, anticorps GST4, anticorps GSTM, anticorps GSTM2-2, anticorps GTHMUS, anticorps Gstb-2, anticorps Gstb2, anticorps GSTIV, anticorps glutathione S-transferase mu 2, anticorps glutathione S-transferase mu 2 (muscle), anticorps glutathione S-transferase Mu 2, anticorps glutathione S-transferase, mu 2, anticorps glutathione S-transferase 2, anticorps Glutathione S-transferase 4, anticorps Gstm2, anticorps GSTM2, anticorps LOC100732167, anticorps gst2, anticorps gst-4
    Sujet
    At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM2 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
    Alias Symbols: GST4, GSTM, GSTM2-2, GTHMUS, MGC117303
    Protein Interaction Partner: UBC, GSTM3, GSTM2, GSTM1,
    Protein Size: 218
    Poids moléculaire
    26 kDa
    ID gène
    2946
    NCBI Accession
    NM_000848, NP_000839
    UniProt
    P28161
    Pathways
    Negative Regulation of Transporter Activity
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