TNNT1 anticorps (Middle Region)
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- Antigène Voir toutes TNNT1 Anticorps
- TNNT1 (Slow Skeletal Troponin T (TNNT1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TNNT1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- WIHQLESEKF DLMAKLKQQK YEINVLYNRI SHAQKFRKGA GKGRVGGRWK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against TNNT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TNNT1
- Top Product
- Discover our top product TNNT1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 278 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TNNT1 (Slow Skeletal Troponin T (TNNT1))
- Autre désignation
- TNNT1 (TNNT1 Produits)
- Synonymes
- anticorps ANM, anticorps NEM5, anticorps STNT, anticorps TNT, anticorps TNTS, anticorps TNNI1, anticorps AW146156, anticorps Tnt, anticorps sTnT, anticorps ssTnT, anticorps Fang2, anticorps tnTs, anticorps Tnnt, anticorps zgc:193831, anticorps zgc:193865, anticorps troponin T1, slow skeletal type, anticorps troponin I1, slow skeletal type, anticorps troponin T1, skeletal, slow, anticorps troponin T1, slow skeletal type S homeolog, anticorps troponin T type 1 (skeletal, slow), anticorps TNNT1, anticorps TNNI1, anticorps Tnnt1, anticorps tnnt1.S, anticorps tnnt1
- Sujet
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TNNT1 is a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year.This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ANM, MGC104241, TNT, STNT, TNTS
Protein Interaction Partner: CCDC136, TFIP11, LDOC1, MORF4L1, TBPL1, TPM3, TPM1, TNNT1, NFE2L2, KRT40, UBC, PI4KA, SERPINA4, OSM, MARS, HSP90AB1, FYN, EEF1G, DDX5, CHD3, BLOC1S2, C2orf44, ZNF768, ZNF250, ZC3H15, NAGK, HMP19, TRA2A, TMEM98, ARMC8, OSBP2, ZKSCAN5, LARP1, NACAD, SNW1, S
Protein Size: 278 - Poids moléculaire
- 33 kDa
- ID gène
- 7138
- NCBI Accession
- NM_003283, NP_003274
- UniProt
- P13805
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