IRF9 anticorps (N-Term)

N° du produit ABIN2777226

Détail du produit anti-IRF9 anticorps

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PWKHAGKQDF REDQDAAFFK AWAIFKGKYK EGDTGGPAVW KTRLRCALNK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ISGF3G. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ISGF3G

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 393 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-IRF9 (ABIN2777226)

Bidwell, Slaney, Withana, Forster, Cao, Loi, Andrews, Mikeska, Mangan, Samarajiwa, de Weerd, Gould, Argani, Möller, Smyth, Anderson, Hertzog, Parker: "Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape." dans: Nature medicine, Vol. 18, Issue 8, pp. 1224-31, (2013) (PubMed).

Schumacher, Lau, Johnson: "Structural basis of core promoter recognition in a primitive eukaryote." dans: Cell, Vol. 115, Issue 4, pp. 413-24, (2003) (PubMed).

Détails sur IRF9

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Autre désignation: ISGF3G (IRF9 Produits)

Synonymes: anticorps IRF-9, anticorps ISGF3, anticorps ISGF3G, anticorps p48, anticorps zgc:92097, anticorps Irf-9, anticorps Isgf3g, anticorps interferon regulatory factor 9, anticorps IRF9, anticorps irf9, anticorps Irf9

Sujet: ISGF3G functions to recruit RNA polymerase II to the promoter of interferon-stimulated genes and requires histone deacetylases. Defects in ISGF3 can cause resistance to IFN-.(2a) treatment.
Alias Symbols: IRF-9, ISGF3, ISGF3G, p48
Protein Interaction Partner: S100A13, MYO1F, TOP1, IRF1, IRF2BP1, DNMT3A, ELAVL1, STAT2, IFNAR2, CREBBP, DACH2, DMRTC2, TLX3, VENTX, ARID3B, NR2E3, POU2F1, HOXC9, TLX2, STAT1, IFNA1, RELA, NFKB1,
Protein Size: 393

Poids moléculaire: 44 kDa

ID gène: 10379

NCBI Accession: NM_006084, NP_006075

UniProt: Q00978

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C