NFE2 anticorps (C-Term)
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- Antigène Voir toutes NFE2 Anticorps
- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Lapin, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFE2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ARGEADRTLE VMRQQLAELY HDIFQHLRDE SGNSYSPEEY VLQQAADGAI
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against Nfe2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Nfe2
- Top Product
- Discover our top product NFE2 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
- Autre désignation
- Nfe2 (NFE2 Produits)
- Synonymes
- anticorps NF-E2, anticorps p45, anticorps 45kDa, anticorps p45NFE2, anticorps p45nf-e2, anticorps nuclear factor, erythroid 2, anticorps nuclear factor, erythroid derived 2, anticorps NFE2, anticorps Nfe2
- Sujet
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Nfe2 is a component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.It binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. It requires MAFK or other small MAF proteins for binding to the NF-E2 motif. It may play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Alias Symbols: 45 kDa, NF-E2, p45, p45NFE2, p45nf-e2
Protein Interaction Partner: Psmd4, Kmt2d, Rbbp5, Wdr5, Ash2l, Men1, Mafk, H3f3a, Crebbp, Mapk8, Trip4, Plrg1, Pdlim4, Zfp292, Gtf2h2, Zscan2, Ubp1, Tsg101, Tial1, Supt4a, Snai1, Kdm5d, Kdm5c, Dpf2, Per1, Kat2b, Mybbp1a, Orc2, Ikbkg, Hoxb4, Hoxa4, Hcls1, Gtf2h1, Foxn2, E4f1, Dlx5, Ci
Protein Size: 373 - Poids moléculaire
- 41 kDa
- ID gène
- 18022
- NCBI Accession
- NM_008685, NP_032711
- UniProt
- Q07279
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