ISL1 anticorps (C-Term)
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- Antigène Voir toutes ISL1 Anticorps
- ISL1 (ISL LIM Homeobox 1 (ISL1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Lapin, Boeuf (Vache), Chien, Cobaye, Mouton, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ISL1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- IMMKQLQQQQ PNDKTNIQGM TGTPMVAASP ERHDGGLQAN PVEVQSYQPP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against ISL1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ISL1
- Top Product
- Discover our top product ISL1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ISL1 (ISL LIM Homeobox 1 (ISL1))
- Autre désignation
- ISL1 (ISL1 Produits)
- Synonymes
- anticorps Xisl-1, anticorps Xislet-1, anticorps islet1, anticorps ISLET-1, anticorps ISLET1, anticorps Isl-1, anticorps islet-1, anticorps isl-1=homeobox, anticorps Islet-1, anticorps ISL LIM homeobox 1 S homeolog, anticorps ISL LIM homeobox 1, anticorps ISL1 transcription factor, LIM/homeodomain, anticorps isl1.S, anticorps ISL1, anticorps Isl1, anticorps isl1
- Sujet
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ISL1 is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation.
Alias Symbols: ISLET1, Isl-1
Protein Interaction Partner: ZNF511, KDM1A, RELA, SMAD3, CDKN2B, CDK6, APP, COPS5, SSBP4, LHX4, LDB2, ISL2, PECR, LDB1, LHX1, LHX3, LMX1A, RLIM, LMO2, ESR1, NR2F1, ISL1,
Protein Size: 349 - Poids moléculaire
- 39 kDa
- ID gène
- 3670
- NCBI Accession
- NM_002202, NP_002193
- UniProt
- P61371
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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