FOSL1 anticorps (Middle Region)

N° du produit ABIN2777265

Détail du produit anti-FOSL1 anticorps

Antigène: FOSL1 (FOS-Like Antigen 1 (FOSL1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Lapin, Cheval, Cobaye, Poisson zèbre (Danio rerio), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOSL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TDFLQAETDK LEDEKSGLQR EIEELQKQKE RLELVLEAHR PICKIPEGAK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 85%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against FOSL1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FOSL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 271 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FOSL1 (ABIN2777265)

Seitz, Schürmann, Pfeilschifter, Frank, Sader: "Identification of the Fra-1 transcription factor in healing skin flaps transplants: a potential role as a negative regulator of VEGF release from keratinocytes." dans: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, Vol. 40, Issue 4, pp. 379-86, (2012) (PubMed).

Kashiwada, Cassel, Colgan, Rothman: "NFIL3/E4BP4 controls type 2 T helper cell cytokine expression." dans: The EMBO journal, Vol. 30, Issue 10, pp. 2071-82, (2011) (PubMed).

Détails sur FOSL1

Antigène: FOSL1 (FOS-Like Antigen 1 (FOSL1))

Autre désignation: FOSL1 (FOSL1 Produits)

Synonymes: anticorps FRA, anticorps FRA1, anticorps fra-1, anticorps AW538199, anticorps Fra1, anticorps Fra-1, anticorps fosl1, anticorps sb:eu506, anticorps si:ch211-145o7.4, anticorps FOS like 1, AP-1 transcription factor subunit, anticorps fos-like antigen 1, anticorps FOS-like antigen 1a, anticorps FOSL1, anticorps Fosl1, anticorps fosl1a

Sujet: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Alias Symbols: FRA1, fra-1, FRA
Protein Interaction Partner: NME7, CREB5, USF1, LDOC1, JUNB, MAFB, MAF, JUN, DDIT3, ATF2, CEBPG, CEBPE, CEBPA, ATF4, ATF3, PARVG, WFDC1, TAB2, ATXN1, MYC, KPNA1, PSMC3, EP300, CREBBP, TRIM24, UBC, HDAC1, CALCOCO1, ATF1, CREB1, SRF, ELK1,
Protein Size: 271

Poids moléculaire: 29 kDa

ID gène: 8061

NCBI Accession: NM_005438, NP_005429

UniProt: P15407