HOXB5 anticorps (N-Term)

N° du produit ABIN2777303

Détail du produit anti-HOXB5 anticorps

Antigène: HOXB5 (Homeobox B5 (HOXB5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXB5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MSSYFVNSFS GRYPNGPDYQ LLNYGSGSSL SGSYRDPAAM HTGSYGYNYN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HOXB5. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 269 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HOXB5 (ABIN2777303)

Fu, Lui, Sham, Cheung, Tam: "HOXB5 expression is spatially and temporarily regulated in human embryonic gut during neural crest cell colonization and differentiation of enteric neuroblasts." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 228, Issue 1, pp. 1-10, (2003) (PubMed).

Détails sur HOXB5

Antigène: HOXB5 (Homeobox B5 (HOXB5))

Autre désignation: HOXB5 (HOXB5 Produits)

Synonymes: anticorps HHO.C10, anticorps HOX2, anticorps HOX2A, anticorps HU-1, anticorps Hox2.1, anticorps AI385717, anticorps Hox-2.1, anticorps ZF-21, anticorps ZF21, anticorps hox-2.1, anticorps hox-B5, anticorps hoxb5, anticorps wu:fc38c09, anticorps z-18, anticorps Ghox-2.1, anticorps Hoxb-5, anticorps HOXB5, anticorps RGD1562292, anticorps hox2, anticorps hu-1, anticorps hox2a, anticorps hox2.1, anticorps hho.c10, anticorps XlHbox4, anticorps hoxb5-A, anticorps homeobox B5, anticorps homeobox B5a, anticorps Hox 5, anticorps homeo box B5, anticorps homeobox B5 S homeolog, anticorps homeobox protein Hox-B5a, anticorps HOXB5, anticorps Hoxb5, anticorps hoxb5a, anticorps hox5, anticorps hoxb5, anticorps hoxb5.S, anticorps LOC101072989

Sujet: HOXB5 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. The exact role of this gene has yet to be determined.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Alias Symbols: HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
Protein Interaction Partner: MAGEA11, CTBP2, CTBP1, TRIM23, UBC,
Protein Size: 269

Poids moléculaire: 30 kDa

ID gène: 3215

NCBI Accession: NM_002147, NP_002138

UniProt: P09067