COPS5 anticorps (N-Term)

N° du produit ABIN2777332

Détail du produit anti-COPS5 anticorps

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Cheval, Lapin, Cobaye, Chien, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS5 est non-conjugé

Application: Western Blotting (WB)

Séquence: AASGSGMAQK TWELANNMQE AQSIDEIYKY DKKQQQEILA AKPWTKDHHY

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against COPS5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human COPS5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 334 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur COPS5

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Autre désignation: COPS5 (COPS5 Produits)

Synonymes: anticorps BcDNA.LD14392, anticorps BcDNA:LD14392, anticorps CG14884, anticorps CH5, anticorps CSN-5, anticorps Csn5, anticorps DCH5, anticorps Dch5, anticorps Dmel\\CG14884, anticorps JAB1, anticorps JAB1/CSN5, anticorps Jab1, anticorps JadBp, anticorps csn5, anticorps dch5, anticorps jab1/csn5, anticorps l(3)89Cf, anticorps l(3)L4032, anticorps l(3)M203, anticorps quo, anticorps COPS5, anticorps MGC76063, anticorps AI303502, anticorps CSN5, anticorps Mov34, anticorps Sgn5, anticorps zgc:73130, anticorps MOV-34, anticorps SGN5, anticorps COP9 signalosome subunit 5, anticorps COP9 signalosome complex subunit 5, anticorps COP9 signalosome subunit 5 S homeolog, anticorps CSN5, anticorps COPS5, anticorps cops5, anticorps CpipJ_CPIJ012314, anticorps Bm1_46585, anticorps VDBG_06932, anticorps LOAG_01443, anticorps csn5, anticorps Cops5, anticorps cops5.S, anticorps csn-5

Sujet: COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CSN5, JAB1, MGC3149, MOV-34, SGN5
Protein Interaction Partner: COPS6, UBC, CUL1, NEDD8, PTGS2, GPS1, LRP1, RANBP9, APP, SIAH1, BACE1, CTNNB1, COPS5, STAT3, CREB3, COPS4, SART3, COPS3, EPB41L1, CAST, KIF5B, PDLIM7, SMAD4, FBXO6, COPS2, TYK2, CDK2, CENPW, CENPT, FBXW4, MYEOV2, COPS8, CHUK, IKBKB, DTL, CD93, DDO, SMAD2,
Protein Size: 334

Poids moléculaire: 37 kDa

ID gène: 10987

NCBI Accession: NM_006837, NP_006828

UniProt: Q92905

Pathways: Cycle Cellulaire