ERCC8 anticorps (C-Term)
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- Antigène Voir toutes ERCC8 Anticorps
- ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Chien, Lapin, Cheval, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ERCC8 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- QELYSGSRDC NILAWVPSLY EPVPDDDETT TKSQLNPAFE DAWSSSDEEG
- Homologie
- Dog: 93%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 79%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against ERCC8. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human ERCC8
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 396 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Cumulative defects in DNA repair pathways drive the PARP inhibitor response in high-grade serous epithelial ovarian cancer cell lines." dans: Oncotarget, Vol. 8, Issue 25, pp. 40152-40168, (2018) (PubMed).
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Cumulative defects in DNA repair pathways drive the PARP inhibitor response in high-grade serous epithelial ovarian cancer cell lines." dans: Oncotarget, Vol. 8, Issue 25, pp. 40152-40168, (2018) (PubMed).
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- Antigène
- ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
- Autre désignation
- ERCC8 (ERCC8 Produits)
- Synonymes
- anticorps zgc:103550, anticorps CKN1, anticorps CSA, anticorps UVSS2, anticorps Ckn1, anticorps 2410022P04Rik, anticorps 2810431L23Rik, anticorps 4631412O06Rik, anticorps B130065P18Rik, anticorps Csa, anticorps excision repair cross-complementation group 8, anticorps ERCC excision repair 8, CSA ubiquitin ligase complex subunit, anticorps excision repaiross-complementing rodent repair deficiency, complementation group 8, anticorps ercc8, anticorps ERCC8, anticorps Ercc8
- Sujet
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ERCC8 (excision repair cross-complementing rodent repair deficiency, complementation group 8 isoform 1) is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcript
Alias Symbols: CKN1, CSA
Protein Interaction Partner: CUL4A, CUL4B, DDB1, RUVBL2, ZNF24, PCNA, H1F0, ERCC6, UVSSA, DDA1, RFWD2, COPS4, COPS6, COPS3, TOP1, TP53, SSBP1, OGG1, MDM2, GTF2H2, CUL5, GPS1, DDB2, COPS2, COPS7A, COPS5, COPS8, RBX1, POLR2A, HMGN1, EP300, UBC, CSNK2B, XAB2, UQCRQ, CBR1,
Protein Size: 396 - Poids moléculaire
- 44 kDa
- ID gène
- 1161
- NCBI Accession
- NM_000082, NP_000073
- UniProt
- Q13216
- Pathways
- Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
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