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SLC26A3 anticorps (Middle Region)

SLC26A3 Reactivité: Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Mouton, Chien, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777377
  • Antigène Voir toutes SLC26A3 Anticorps
    SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))
    Épitope
    • 3
    • 2
    • 1
    • 1
    Middle Region
    Reactivité
    Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Mouton, Chien, Cobaye
    Hôte
    • 13
    • 2
    Lapin
    Clonalité
    • 14
    • 1
    Polyclonal
    Conjugué
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SLC26A3 est non-conjugé
    Application
    • 8
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    DAVLHILMKK DYSTSKFNPS QEKDGKIDFT INTNGGLRNR VYEVPVETKF
    Homologie
    Cow: 100%, Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%, Sheep: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SLC26A3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human SLC26A3
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 764 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kjærgaard, Damm, Chang, Riis, Rasmussen, Hytting-Andreasen, Krug, Schulzke, Bindslev, Hansen: "Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?" dans: International journal of molecular sciences, Vol. 21, Issue 5, (2020) (PubMed).

  • Antigène
    SLC26A3 (Solute Carrier Family 26, Member 3 (SLC26A3))
    Autre désignation
    SLC26A3 (SLC26A3 Produits)
    Synonymes
    anticorps CLD, anticorps DRA, anticorps 9030623B18Rik, anticorps 9130013M11Rik, anticorps AV376035, anticorps Dra, anticorps si:dkey-31f5.2, anticorps SLC26A3, anticorps solute carrier family 26 member 3, anticorps solute carrier family 26, member 3, anticorps solute carrier family 26 (anion exchanger), member 3, anticorps SLC26A3, anticorps Slc26a3, anticorps slc26a3.1
    Sujet
    SLC26A3 is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.The protein encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. Mutations in this gene have been associated with congenital chloride diarrhea. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CLD, DRA
    Protein Interaction Partner: SLC9A3R1, SLC9A3R2,
    Protein Size: 764
    Poids moléculaire
    84 kDa
    ID gène
    1811
    NCBI Accession
    NM_000111, NP_000102
    UniProt
    P40879
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