PHOX2A anticorps (N-Term)
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- Antigène Voir toutes PHOX2A Anticorps
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PHOX2A est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- AVPYKFFPEP SGLHEKRKQR RIRTTFTSAQ LKELERVFAE THYPDIYTRE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against PHOX2A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PHOX2A
- Top Product
- Discover our top product PHOX2A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 284 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
- Autre désignation
- PHOX2A (PHOX2A Produits)
- Synonymes
- anticorps ARIX, anticorps CFEOM2, anticorps FEOM2, anticorps NCAM2, anticorps PMX2A, anticorps Arix, anticorps Phox2, anticorps Pmx2, anticorps Pmx2a, anticorps arix, anticorps sou, anticorps zgc:77364, anticorps phox2, anticorps xphox2a, anticorps paired like homeobox 2a, anticorps paired-like homeobox 2a, anticorps paired like homeobox 2a S homeolog, anticorps PHOX2A, anticorps Phox2a, anticorps phox2a, anticorps phox2a.S
- Sujet
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PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
Protein Interaction Partner: SP1, PHOX2A, HAND2, PRKACA, ATF6B, CREBBP, JUN,
Protein Size: 284 - Poids moléculaire
- 30 kDa
- ID gène
- 401
- NCBI Accession
- NM_005169, NP_005160
- UniProt
- O14813
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