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PHOX2A anticorps (N-Term)

PHOX2A Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777426
  • Antigène Voir toutes PHOX2A Anticorps
    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
    Épitope
    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 31
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)
    Hôte
    • 27
    • 3
    • 1
    Lapin
    Clonalité
    • 29
    • 2
    Polyclonal
    Conjugué
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PHOX2A est non-conjugé
    Application
    • 25
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    AVPYKFFPEP SGLHEKRKQR RIRTTFTSAQ LKELERVFAE THYPDIYTRE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against PHOX2A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human PHOX2A
    Top Product
    Discover our top product PHOX2A Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 284 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
    Autre désignation
    PHOX2A (PHOX2A Produits)
    Synonymes
    anticorps ARIX, anticorps CFEOM2, anticorps FEOM2, anticorps NCAM2, anticorps PMX2A, anticorps Arix, anticorps Phox2, anticorps Pmx2, anticorps Pmx2a, anticorps arix, anticorps sou, anticorps zgc:77364, anticorps phox2, anticorps xphox2a, anticorps paired like homeobox 2a, anticorps paired-like homeobox 2a, anticorps paired like homeobox 2a S homeolog, anticorps PHOX2A, anticorps Phox2a, anticorps phox2a, anticorps phox2a.S
    Sujet
    PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
    Protein Interaction Partner: SP1, PHOX2A, HAND2, PRKACA, ATF6B, CREBBP, JUN,
    Protein Size: 284
    Poids moléculaire
    30 kDa
    ID gène
    401
    NCBI Accession
    NM_005169, NP_005160
    UniProt
    O14813
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