TOLLIP anticorps (C-Term)

N° du produit ABIN2777431

Détail du produit anti-TOLLIP anticorps

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOLLIP est non-conjugé

Application: Western Blotting (WB)

Séquence: MATTVSTQRG PVYIGELPQD FLRITPTQQQ RQVQLDAQAA QQLQYGGAVG

Homologie: Cow: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 83%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TOLLIP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TOLLIP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 274 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TOLLIP (ABIN2777431)

Schimming, Parwez, Petrasch-Parwez, Nothnagel, Epplen, Hoffjan: "Association of toll-interacting protein gene polymorphisms with atopic dermatitis." dans: BMC dermatology, Vol. 7, pp. 3, (2007) (PubMed).

Détails sur TOLLIP

Antigène: TOLLIP (Toll Interacting Protein (TOLLIP))

Autre désignation: TOLLIP (TOLLIP Produits)

Synonymes: anticorps IL-1RAcPIP, anticorps 4930403G24Rik, anticorps 4931428G15Rik, anticorps fk22a02, anticorps im:7145391, anticorps wu:fk22a02, anticorps zgc:76985, anticorps TOLLIP, anticorps GB17961, anticorps tollip, anticorps tollip1, anticorps tollipa, anticorps TOLIP, anticorps toll interacting protein, anticorps toll-interacting protein, anticorps toll-interacting protein-like, anticorps toll interacting protein L homeolog, anticorps toll interacting protein S homeolog, anticorps Toll-interleukine I receptor interacting protein I, anticorps TOLLIP, anticorps Tollip, anticorps tollip, anticorps LOC552034, anticorps LOC100169858, anticorps tollip.L, anticorps tollip.S, anticorps LOC100136122

Sujet: TOLLIP is component of the signaling pathway of IL-1 and Toll-like receptors. It Inhibits cell activation by microbial products. It also recruits IRAK1 to the IL-1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity.
Alias Symbols: FLJ33531, IL-1RAcPIP
Protein Interaction Partner: RBPMS, TOM1, DAZAP2, UBC, SIAH1, PRR20A, WDYHV1, CPSF6, DAB1, ATG8, MAP1LC3A, SQSTM1, NBR1, VPS35, OXR1, VPS29, CYHR1, NMI, APEH, RHOXF2, TOM1L1, IRAK1, PINK1, INTS4P2, SNX8, TRIP6, UBD, TGFBR1, ATXN1, SMAD7, TOM1L2, TOLLIP, GGA1, GGA3, GGA2, TRAF6, RAC1,
Protein Size: 274

Poids moléculaire: 30 kDa

ID gène: 54472

NCBI Accession: NM_019009, NP_061882

UniProt: Q9H0E2