NR5A1 anticorps (Middle Region)
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- Antigène Voir toutes NR5A1 Anticorps
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Cobaye, Cheval, Lapin, Chien, Boeuf (Vache), Mouton
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR5A1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- AVPGAHGPLA GYLYPAFPGR AIKSEYPEPY ASPPQPGLPY GYPEPFSGGP
- Homologie
- Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 79%, Rabbit: 85%, Rat: 92%, Sheep: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against NR5A1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human NR5A1
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 461 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
- Autre désignation
- NR5A1 (NR5A1 Produits)
- Synonymes
- anticorps AD4BP, anticorps ELP, anticorps FTZ1, anticorps FTZF1, anticorps POF7, anticorps SF-1, anticorps SF1, anticorps SPGF8, anticorps SRXY3, anticorps Ad4BP, anticorps ELP-3, anticorps Ftz-F1, anticorps Ftzf1, anticorps Ad4BP/SF-1, anticorps Ad4bp, anticorps Sf-1, anticorps NR5A1, anticorps sf-1, anticorps elp, anticorps sf1, anticorps ftz1, anticorps ad4bp, anticorps ftzf1, anticorps SF-1/Ad4BP, anticorps SI:zC167P9.2, anticorps ff1d, anticorps nr5a2l, anticorps nuclear receptor subfamily 5 group A member 1, anticorps nuclear receptor subfamily 5, group A, member 1, anticorps nuclear receptor subfamily 5 group A member 1 L homeolog, anticorps nuclear receptor subfamily 6 group A member 1, anticorps nuclear receptor subfamily 5, group A, member 1b, anticorps NR5A1, anticorps Nr5a1, anticorps nr5a1.L, anticorps nr5a1, anticorps NR6A1, anticorps nr5a1b
- Sujet
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NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1, POF7, SPGF8, SRXY3
Protein Interaction Partner: NCK2, NR0B1, RAD54L2, THOC2, ALYREF, EIF4A3, DDX39B, UBC, BARD1, ELAVL1, TCF7L2, CTNNB1, CREBBP, CXXC1, PNRC2, SOX8, PIAS1, ZNF653, TRERF1, EDF1, GATA4, GTF2B, SOX2, SOX9, TBX19, NCOA1, NRIP1, PITX1, SMARCD3, PROX1, AR, SP1, NFYA, MAPK1, JUN, NFKB2,
Protein Size: 461 - Poids moléculaire
- 52 kDa
- ID gène
- 2516
- NCBI Accession
- NM_004959, NP_004950
- UniProt
- Q13285
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Maintenance of Protein Location
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