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DREAM anticorps (N-Term)

KCNIP3 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio), Porc WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777506
  • Antigène Voir toutes DREAM (KCNIP3) Anticorps
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    Épitope
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 50
    • 30
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio), Porc
    Hôte
    • 43
    • 7
    • 2
    Lapin
    Clonalité
    • 48
    • 4
    Polyclonal
    Conjugué
    • 29
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DREAM est non-conjugé
    Application
    • 47
    • 22
    • 18
    • 13
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    STVRHQPEGL DQLQAQTKFT KKELQSLYRG FKNECPTGLV DEDTFKLIYA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against CSEN. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human CSEN
    Top Product
    Discover our top product KCNIP3 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 256 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." dans: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

  • Antigène
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    Autre désignation
    CSEN (KCNIP3 Produits)
    Sujet
    CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
    Alias Symbols: CSEN, DREAM, KCHIP3
    Protein Interaction Partner: MAVS, CD177, IGLV3-25, IL6ST, IGF1R, KCND2, CLN3, CALM2, KCNIP3, PPP3CA, GRK6, ADRBK1, UBE2I, UBC, PCBD2, TARBP2, PSEN2, CASP3, CREM, CREB1, PSEN1, CRK,
    Protein Size: 256
    Poids moléculaire
    29 kDa
    ID gène
    30818
    NCBI Accession
    NM_013434, NP_038462
    UniProt
    Q9Y2W7
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