PAX7 anticorps (C-Term)

N° du produit ABIN2777560

Détail du produit anti-PAX7 anticorps

Antigène: PAX7 (Paired Box 7 (PAX7))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAX7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: QADFSISPLH GGLDSATSIS ASCSQRADSI KPGDSLPTSQ AYCPPTYSTT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PAX7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of PAX7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 520 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PAX7 (ABIN2777560)

Gautam, Nirwane, Yao: "Laminin differentially regulates the stemness of type I and type II pericytes." dans: Stem cell research & therapy, Vol. 8, Issue 1, pp. 28, (2017) (PubMed).

Czerwinska, Nowacka, Aszer, Gawrzak, Archacka, Fogtman, Iwanicka-Nowicka, Jańczyk-Ilach, Koblowska, Ciemerych, Grabowska: "Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7." dans: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 21, pp. 2931-2942, (2016) (PubMed).

Wehling-Henricks, Li, Lindsey, Wang, Welc, Ramos, Khanlou, Kuro-O, Tidball: "Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy." dans: Human molecular genetics, Vol. 25, Issue 12, pp. 2465-2482, (2016) (PubMed).

Akahori, Karmali, Polavarapu, Lyle, Weiss, Shin, Husain, Naqvi, Van Dam, Habib, Choi, King, Pachura, Taylor, Lefer, Finn: "CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury." dans: Nature communications, Vol. 6, pp. 7792, (2015) (PubMed).

McDonald, Hebert, McLoon: "Sparing of the extraocular muscles in mdx mice with absent or reduced utrophin expression: A life span analysis." dans: Neuromuscular disorders : NMD, Vol. 25, Issue 11, pp. 873-87, (2015) (PubMed).

Caldow, Thomas, Dale, Tomkinson, Buckley, Cameron-Smith: "Early myogenic responses to acute exercise before and after resistance training in young men." dans: Physiological reports, Vol. 3, Issue 9, (2015) (PubMed).

Détails sur PAX7

Antigène: PAX7 (Paired Box 7 (PAX7))

Autre désignation: PAX7 (PAX7 Produits)

Synonymes: anticorps PAX7, anticorps HUP1, anticorps PAX7B, anticorps RMS2, anticorps pax-7, anticorps PAX-7, anticorps RGD1564360, anticorps Pax-7, anticorps pax7, anticorps pax7c, anticorps pax7d, anticorps pax7e, anticorps paired box 7, anticorps paired box protein Pax-7, anticorps paired box 7 L homeolog, anticorps paired box 7a, anticorps PAX7, anticorps pax7.L, anticorps LOC536229, anticorps Pax7, anticorps pax7a

Sujet: PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.
Alias Symbols: FLJ37460, HUP1, PAX7B, RMS2
Protein Interaction Partner: TRIM27, MYOD1, Dlg4, WDR5, ASH2L, HIRA, Ubc,
Protein Size: 520

Poids moléculaire: 57 kDa

ID gène: 5081

NCBI Accession: NM_002584, NP_002575

UniProt: P23759