ACSL1 anticorps (C-Term)

N° du produit ABIN2777590

Détail du produit anti-ACSL1 anticorps

Antigène: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACSL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GSFEELCRNK DVKKAILEDM VRLGKDSGLK PFEQVKGITL HPELFSIDNG

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ACSL1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ACSL1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 698 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ACSL1 (ABIN2777590)

Golej, Askari, Kramer, Barnhart, Vivekanandan-Giri, Pennathur, Bornfeldt: "Long-chain acyl-CoA synthetase 4 modulates prostaglandin E? release from human arterial smooth muscle cells." dans: Journal of lipid research, Vol. 52, Issue 4, pp. 782-93, (2011) (PubMed).

Détails sur ACSL1

Antigène: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Autre désignation: ACSL1 (Acsl1 Produits)

Synonymes: anticorps ACS1, anticorps FACL1, anticorps FACL2, anticorps LACS, anticorps LACS1, anticorps LACS2, anticorps Acas, anticorps Acas1, anticorps Acs, anticorps FACS, anticorps Facl2, anticorps ACS, anticorps COAA, anticorps zgc:110081, anticorps CER8, anticorps ECERIFERUM 8, anticorps LONG-CHAIN ACYL-COA SYNTHASE 1, anticorps T8I13.8, anticorps F13F21.14, anticorps F13F21_14, anticorps LATERAL ROOT DEVELOPMENT 2, anticorps LRD2, anticorps long-chain acyl-CoA synthetase 2, anticorps acyl-CoA synthetase long chain family member 1, anticorps acyl-CoA synthetase long-chain family member 1, anticorps acyl-CoA synthetase long chain family member 1a, anticorps AMP-dependent synthetase and ligase family protein, anticorps long-chain acyl-CoA synthetase 2, anticorps ACSL1, anticorps Acsl1, anticorps acsl1a, anticorps LACS1, anticorps LACS2

Sujet: ACSL1 encodes an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACS1, FACL1, FACL2, LACS, LACS1, LACS2
Protein Interaction Partner: SUMO2, PARK2, ATP4A, UBC, NR3C2, ECT2, UBD,
Protein Size: 698

Poids moléculaire: 78 kDa

ID gène: 2180

NCBI Accession: NM_001995, NP_001986

UniProt: P33121

Pathways: Regulation of Lipid Metabolism by PPARalpha