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Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (N-Term) anticorps

L’anticorps anti-Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial Polyclonal Lapin est utilisé pour la détection de Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial dans des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Cheval. Il a été validé pour WB.
N° du produit ABIN2777593
534,11 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 8 jours ouvrables

Aperçu rapide pour Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD) (N-Term) anticorps (ABIN2777593)

Antigène

Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)

Reactivité

  • 87
  • 51
  • 45
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Cheval

Hôte

  • 84
  • 5
  • 2
Lapin

Clonalité

  • 56
  • 34
Polyclonal

Conjugué

  • 38
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Inconjugué

Application

  • 62
  • 32
  • 30
  • 26
  • 23
  • 19
  • 14
  • 13
  • 11
  • 8
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 15
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    AAGFGRCCRV LRSISRFHWR SQHTKANRQR EPGLGFSFEF TEQQKEFQAT

    Homologie

    Cow: 92%, Horse: 92%, Human: 100%, Mouse: 91%, Rat: 91%

    Attributs du produit

    This is a rabbit polyclonal antibody against ACADM. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human ACADM
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 421 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (MCAD)

    Autre désignation

    ACADM

    Sujet

    ACADM Is the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: ACAD1, MCAD, MCADH
    Protein Interaction Partner: SUMO2, SUMO3, UBC, MDM2, STRAP, HDAC1, UBD, CUL3, SUMO4, CALM1, USP50, USP20, ACADM,
    Protein Size: 421

    Poids moléculaire

    46 kDa

    ID gène

    34

    NCBI Accession

    NM_000016, NP_000007

    UniProt

    P11310
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