DUSP12 anticorps (N-Term)
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- Antigène Voir toutes DUSP12 Anticorps
- DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Chien, Cheval, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DUSP12 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- VEDLWRLFVP ALDKPETDLL SHLDRCVAFI GQARAEGRAV LVHCHAGVSR
- Homologie
- Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against DUSP12. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human DUSP12
- Top Product
- Discover our top product DUSP12 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 340 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
- Autre désignation
- DUSP12 (DUSP12 Produits)
- Synonymes
- anticorps DUSP12, anticorps dusp12, anticorps zgc:114069, anticorps MGC154526, anticorps DUSP1, anticorps YVH1, anticorps 1190004O14Rik, anticorps AA027408, anticorps AW049275, anticorps ESTM36, anticorps LMW-DSP4, anticorps T-DSP4, anticorps VH1, anticorps mVH1, anticorps GKAP, anticorps dual specificity phosphatase 12, anticorps dual specificity phosphatase 12 L homeolog, anticorps Dual specificity protein phosphatase 12, anticorps dual specificity protein phosphatase 12, anticorps DUSP12, anticorps dusp12, anticorps dusp12.L, anticorps GL50803_36315, anticorps MGYG_01770, anticorps Dusp12
- Sujet
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DUSP12 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
Alias Symbols: DUSP1, YVH1
Protein Interaction Partner: PPP2R3B, HSPB8, RABAC1, CALCOCO2, USO1, EIF5, CCNH, UBC, APP, NR1H2, KIAA1377, MBD6, PTN,
Protein Size: 340 - Poids moléculaire
- 38 kDa
- ID gène
- 11266
- NCBI Accession
- NM_007240, NP_009171
- UniProt
- Q9UNI6
- Pathways
- Regulation of Carbohydrate Metabolic Process
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